IL-28 Antibody (D-12): sc-137151
- IL-28 Antibody (D-12) is a mouse monoclonal IgG1 κ IL-28 antibody, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 10-189 mapping within an internal region of IL-28B of mouse origin
- IL-28 Antibody (D-12) is recommended for detection of IL-28A and IL-28B of mouse origin by WB, IP, IF and ELISA
- Anti-IL-28 Antibody (D-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for IL-28 Antibody (D-12) for WB applications. These reagents are now offered in bundles with IL-28 Antibody (D-12) (see ordering information below).
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SEE ALSO...
IL-28 Antibody (D-12) is a mouse monoclonal IgG1 kappa light chain antibody that detects IL-28 of mouse origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IL-28 (D-12) antibody is available in non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. IL-28, also known as interleukin-28, plays a crucial role in immune response, particularly in antiviral defense, by promoting immune cell activation and enhancing cytokine production. This function is vital for combating viral infections, making IL-28 a significant target for research in immunology and therapeutic development. IL-28 interacts with specific receptors, such as IL-28 receptor, which is essential for mediating biological effects, further underscoring the importance of studying IL-28 in immune regulation and potential disease treatment.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
IL-28 Antibody (D-12) References:
- IL-28, IL-29 and their class II cytokine receptor IL-28R. | Sheppard, P., et al. 2003. Nat Immunol. 4: 63-8. PMID: 12469119
- Interleukin-10 and related cytokines and receptors. | Pestka, S., et al. 2004. Annu Rev Immunol. 22: 929-79. PMID: 15032600
- The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain. | Donnelly, RP., et al. 2004. J Leukoc Biol. 76: 314-21. PMID: 15123776
- A new member of the interleukin 10-related cytokine family encoded by a poxvirus. | Bartlett, NW., et al. 2004. J Gen Virol. 85: 1401-1412. PMID: 15166422
- The IL-10R2 binding hot spot on IL-22 is located on the N-terminal helix and is dependent on N-linked glycosylation. | Logsdon, NJ., et al. 2004. J Mol Biol. 342: 503-14. PMID: 15327950
- Interferons, interferon-like cytokines, and their receptors. | Pestka, S., et al. 2004. Immunol Rev. 202: 8-32. PMID: 15546383
- IL-28 and IL-29: newcomers to the interferon family. | Uzé, G. and Monneron, D. 2007. Biochimie. 89: 729-34. PMID: 17367910
- IL-28 elicits antitumor responses against murine fibrosarcoma. | Numasaki, M., et al. 2007. J Immunol. 178: 5086-98. PMID: 17404291
- IL-28A, IL-28B, and IL-29: promising cytokines with type I interferon-like properties. | Witte, K., et al. 2010. Cytokine Growth Factor Rev. 21: 237-51. PMID: 20655797
- The IL-28 genotype: how it will affect the care of patients with hepatitis C virus infection. | Pearlman, BL. 2011. Curr Gastroenterol Rep. 13: 78-86. PMID: 21080244
- The Effect of IL-22 and IL-28 in Induction of Type 1 Regulatory T (Tr1) Cells. | Arasteh, J., et al. 2015. Iran J Allergy Asthma Immunol. 14: 158-67. PMID: 25780882
- The Novel Use of IL-28 as an Effective Radiosensitizer in Pancreatic Cancer. | Chen, X., et al. 2023. Anticancer Res. 43: 1885-1890. PMID: 37097692
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IL-28 Antibody (D-12) | sc-137151 | 200 µg/ml | $316.00 | |||
IL-28 Antibody (D-12): m-IgG Fc BP-HRP Bundle | sc-527123 | 200 µg Ab; 10 µg BP | $354.00 | |||
IL-28 Antibody (D-12): m-IgG1 BP-HRP Bundle | sc-532496 | 200 µg Ab; 20 µg BP | $354.00 | |||
IL-28 Antibody (D-12) AC | sc-137151 AC | 500 µg/ml, 25% agarose | $416.00 | |||
IL-28 Antibody (D-12) HRP | sc-137151 HRP | 200 µg/ml | $316.00 | |||
IL-28 Antibody (D-12) FITC | sc-137151 FITC | 200 µg/ml | $330.00 | |||
IL-28 Antibody (D-12) PE | sc-137151 PE | 200 µg/ml | $343.00 | |||
IL-28 Antibody (D-12) Alexa Fluor® 488 | sc-137151 AF488 | 200 µg/ml | $357.00 | |||
IL-28 Antibody (D-12) Alexa Fluor® 546 | sc-137151 AF546 | 200 µg/ml | $357.00 | |||
IL-28 Antibody (D-12) Alexa Fluor® 594 | sc-137151 AF594 | 200 µg/ml | $357.00 | |||
IL-28 Antibody (D-12) Alexa Fluor® 647 | sc-137151 AF647 | 200 µg/ml | $357.00 | |||
IL-28 Antibody (D-12) Alexa Fluor® 680 | sc-137151 AF680 | 200 µg/ml | $357.00 | |||
IL-28 Antibody (D-12) Alexa Fluor® 790 | sc-137151 AF790 | 200 µg/ml | $357.00 |