IL-1 beta/IL1B Antibody (E7-2-hIL1β): sc-32294

IL-1β Antibody (E7-2-hIL1β) is a mouse monoclonal IgG2b kappa light chain antibody that detects human IL-1β by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). IL-1β monoclonal antibody (E7-2-hIL1β) is available in non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. IL-1β is a key pro-inflammatory cytokine mediating immune responses and inflammation. IL-1β is primarily secreted by activated macrophages and activates T and B lymphocytes, as well as natural killer (NK) cells. IL-1β resides in the cytoplasm and releases upon cellular activation, binding to IL-1 receptor to initiate signaling pathways that produce other inflammatory mediators. This cytoplasmic location enables rapid response to inflammatory stimuli, making IL-1β essential in body defense mechanisms. Dysregulation of IL-1β production has been linked to various conditions, including rheumatoid arthritis, inflammatory bowel disease, and atherosclerosis, highlighting IL-1β′s significance in health and disease.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-IL-1 beta/IL1B Antibody (E7-2-hIL1β) has 133 citations in a variety of scientific publications.

Primary antibodies like Anti-IL-1 beta/IL1B Antibody (E7-2-hIL1β) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

IL-1 beta/IL1B Antibody (E7-2-hIL1β) Specifications

Alternate Product Name: IL-1β

Product Clone Name: E7-2-hIL1β

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids:

Epitope Target: IL-1β

Epitope Species: human

Product Reactivity/Detection: IL-1β

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P)

Vialing Information: Each vial contains 200 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 133 citations in various scientific publications

Available Conjugates/Forms for IL-1 beta/IL1B Antibody (E7-2-hIL1β): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin