IL-1α Antibody (1F3B3): sc-32814

IL-1α Antibody (1F3B3) is a mouse monoclonal IgG antibody that detects interleukin-1α in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-IL-1α antibody (1F3B3) recognizes a pivotal cytokine that plays a crucial role in mediating inflammatory responses and regulating immune functions. IL-1α is primarily produced by activated macrophages and is found in various tissues, including the brain, liver, and lungs, where IL-1α can influence local immune responses. IL-1α′s ability to bind to the IL-1 receptor initiates a cascade of signaling events that lead to the activation of immune cells, such as T and B lymphocytes, as well as natural killer cells. This activation is essential for the production of other cytokines, including IL-2, which is vital for T cell proliferation. IL-1α is involved in the pathogenesis of several inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease, highlighting IL-1α′s importance as a therapeutic target. Anti-IL-1α antibody (1F3B3) serves as an invaluable tool for researchers studying the intricate roles of this cytokine in both health and disease.

The preferred IL-1α antibody is IL-1α Antibody (G-10): sc-271618.