IL-1α Antibody (ALF-161): sc-12741
- IL-1α Antibody (ALF-161) is a Armenian hamster monoclonal IgG IL-1α antibody, cited in 8 publications, provided at 200 µg/ml
- raised against full length purified recombinant IL-1α of mouse origin
- IL-1 alpha Antibody (ALF-161) is recommended for detection of IL-1α of mouse, rat and human origin by WB, IP, IF, FCM and ELISA
- Anti-IL-1 alpha Antibody (ALF-161) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also provided azide-free for neutralization, sc-12741 L, 200 µg/0.1 ml
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IL-1α Antibody (ALF-161). This work is in progress.
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IL-1α Antibody (ALF-161) is a hamster monoclonal IgG antibody that detects IL-1α of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). IL-1α Antibody (ALF-161) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. IL-1α plays a pivotal role in the immune response and inflammation, acting as a key mediator that influences the activity of T and B lymphocytes as well as natural killer (NK) cells. IL-1α is primarily located in the cytoplasm of cells and can be released upon cell activation, which is crucial for mediating inflammatory responses. IL-1α presence in the cytoplasm allows for rapid release during inflammatory stimuli, enabling swift communication between immune cells and the surrounding tissue. IL-1α is involved in various physiological processes, including kidney development and cartilage degradation, and has been implicated in several pathological conditions such as rheumatoid arthritis, inflammatory bowel disease, and atherosclerosis. IL-1α binding to the same receptor as IL-1β, despite their distinct genetic origins, underscores IL-1α importance in orchestrating a coordinated immune response.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IL-1α Antibody (ALF-161) | sc-12741 | 200 µg/ml | $322.00 | |||
IL-1α Antibody (ALF-161) L | sc-12741 L | 200 µg/0.1 ml | $322.00 | |||
IL-1α Antibody (ALF-161) AC | sc-12741 AC | 500 µg/ml, 25% agarose | $424.00 | |||
IL-1α Antibody (ALF-161) HRP | sc-12741 HRP | 200 µg/ml | $322.00 | |||
IL-1α Antibody (ALF-161) FITC | sc-12741 FITC | 200 µg/ml | $336.00 | |||
IL-1α Antibody (ALF-161) PE | sc-12741 PE | 200 µg/ml | $349.00 | |||
IL-1α Antibody (ALF-161) Alexa Fluor® 488 | sc-12741 AF488 | 200 µg/ml | $364.00 | |||
IL-1α Antibody (ALF-161) Alexa Fluor® 546 | sc-12741 AF546 | 200 µg/ml | $364.00 | |||
IL-1α Antibody (ALF-161) Alexa Fluor® 594 | sc-12741 AF594 | 200 µg/ml | $364.00 | |||
IL-1α Antibody (ALF-161) Alexa Fluor® 647 | sc-12741 AF647 | 200 µg/ml | $364.00 | |||
IL-1α Antibody (ALF-161) Alexa Fluor® 680 | sc-12741 AF680 | 200 µg/ml | $364.00 | |||
IL-1α Antibody (ALF-161) Alexa Fluor® 790 | sc-12741 AF790 | 200 µg/ml | $364.00 |