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IL-11R alpha Antibody (H-3): sc-393227

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Datasheets
  • IL-11Rα Antibody (H-3) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 403-432 at the C-terminus of IL-11Rα of mouse origin
  • recommended for detection of IL-11Rα of mouse and rat origin by WB, IP, IF and ELISA
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for IL-11Rα Antibody (H-3) for WB applications. These reagents are now offered in bundles with IL-11Rα Antibody (H-3) (see ordering information below).
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    IL-11Rα Antibody (H-3) is a mouse monoclonal IgG2a antibody that detects IL-11Rα in mouse and rat samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IL-11Rα, a crucial component of the interleukin-11 signaling pathway, plays a significant role in regulating immune responses and hematopoiesis. IL-11Rα is primarily located on the surface of various cell types, including mesenchymal and hematopoietic progenitor cells, where IL-11Rα facilitates IL-11 binding, leading to downstream signaling pathway activation that promotes cell proliferation and differentiation. IL-11Rα′s cellular location is essential for proper immune and skeletal system functioning, influencing processes such as inflammation and tissue repair. Additionally, IL-11Rα′s interaction with co-receptor gp130 is vital for high-affinity binding and subsequent signal transduction, underscoring intricate regulatory mechanisms that govern cellular responses to cytokines. With IL-11Rα′s ability to modulate critical biological processes in both normal physiology and pathological conditions, anti-IL-11Rα antibody (H-3) serves as an invaluable tool for researchers studying cytokine signaling and its implications in health and disease.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Contains Mercury: All HRP conjugates (including bundle forms) contain thiomersal, a mercury compound. Do not dispose in trash. Dispose as hazardous chemical waste according to local, state and federal regulations.

    Download thiomersal SDS

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    IL-11Rα Antibody (H-3)

    sc-393227
    200 µg/ml
    $322.00

    IL-11Rα Antibody (H-3): m-IgG Fc BP-HRP Bundle

    sc-538171
    200 µg Ab; 10 µg BP
    $361.00

    IL-11Rα Antibody (H-3): m-IgGκ BP-HRP Bundle

    sc-535731
    200 µg Ab; 40 µg BP
    $361.00

    IL-11Rα Antibody (H-3): m-IgG2a BP-HRP Bundle

    sc-548224
    200 µg Ab; 10 µg BP
    $361.00

    IL-11Rα (H-3) Neutralizing Peptide

    sc-393227 P
    100 µg/0.5 ml
    $69.00

    What application is the blocking peptide sc-393227 P appropriate for?

    Asked by: Cweed
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
    • y_2026, m_11, d_9, h_6CST
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    Rated 5 out of 5 by HC from Great Western blot data of ILGreat Western blot data of IL-11R expression in non-transfected 293T, mouse IL-11R transfected 293T and 3T3-L1 whole cell lysates. -SCBT QC
    Date published: 2013-02-27
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    IL-11Rα Antibody (H-3) is rated 5.0 out of 5 by 1.
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