


IL-11Rα Antibody (B-7) is a mouse monoclonal IgG2a antibody that detects IL-11Rα in mouse and rat samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IL-11Rα, a crucial component of the interleukin-11 signaling pathway, plays a significant role in regulating immune responses and hematopoiesis. IL-11Rα (B-7) antibody targets this receptor primarily on the surface of various cell types, including mesenchymal and hematopoietic progenitor cells, where IL-11Rα facilitates IL-11 binding, leading to downstream signaling cascades that promote cell proliferation and differentiation. IL-11Rα expression is essential for proper immune system function and tissue homeostasis maintenance. IL-11Rα interaction with gp130 co-receptor is critical for high-affinity binding and subsequent signal transduction, underscoring IL-11Rα′s role in mediating IL-11 biological effects. Anti-IL-11Rα antibody (B-7) serves as an invaluable tool for researchers investigating cytokine signaling mechanisms and their implications in various physiological and pathological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IL-11Rα Antibody (B-7) | sc-393057 | 200 µg/ml | $322.00 | |||
IL-11Rα Antibody (B-7): m-IgG Fc BP-HRP Bundle | sc-538128 | 200 µg Ab; 10 µg BP | $361.00 | |||
IL-11Rα Antibody (B-7): m-IgGκ BP-HRP Bundle | sc-535685 | 200 µg Ab; 40 µg BP | $361.00 | |||
IL-11Rα Antibody (B-7): m-IgG2a BP-HRP Bundle | sc-548212 | 200 µg Ab; 10 µg BP | $361.00 | |||
IL-11Rα (B-7) Neutralizing Peptide | sc-393057 P | 100 µg/0.5 ml | $69.00 |