IL-10 Antibody (23738.11): sc-57244
- IL-10 Antibody (23738.11) is a mouse monoclonal IgG2b, cited in 1 publications, provided at 100 µg/ml
- raised against full length IL-10 of human origin
- recommended for detection of IL-10 of human origin by WB and ELISA
- See IL-10 (E-10): sc-8438 for IL-10 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IL-10 Antibody (23738.11). This work is in progress.
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SEE ALSO...
IL-10 Antibody (23738.11) is a mouse monoclonal IgG2b antibody that detects interleukin-10 in human samples through applications such as western blotting (WB) and enzyme-linked immunosorbent assay (ELISA). IL-10 is a crucial cytokine primarily secreted by TH2 clones, playing a significant role in immune regulation by suppressing pro-inflammatory cytokine production from TH1 clones in response to antigens presented by monocyte and macrophage antigen presenting cells. This suppression helps maintain immune homeostasis and prevents excessive inflammatory responses that can lead to tissue damage. IL-10 exerts effects by binding to the IL-10 receptor, a glycoprotein induced in macrophages and fibroblasts upon lipopolysaccharide stimulation, highlighting importance in modulating immune responses during infections and inflammatory conditions. Anti-IL-10 antibody (23738.11) proves particularly valuable for researchers studying IL-10′s role in various diseases, including elevated expression in HIV-1 infected individuals, where IL-10 has been implicated in disease progression. With detection capabilities for both human and murine IL-10, which share significant sequence identity, anti-IL-10 antibody (23738.11) serves as an essential tool for advancing understanding of cytokine signaling and immune regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IL-10 Antibody (23738.11) | sc-57244 | 100 µg/ml | $322.00 |