IKK alpha Antibody (C-6): sc-166231
- IKK alpha Antibody (C-6) is a mouse monoclonal IgG1 κ, cited in 10 publications, provided at 200 µg/ml
- raised against amino acids 248-452 mapping at the C-terminus of IKKα of human origin
- recommended for detection of IKKα of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See IKK alpha (B-8): sc-7606 for IKK alpha antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for IKK alpha Antibody (C-6) for WB and IHC(P) applications. These reagents are now offered in bundles with IKK alpha Antibody (C-6) (see ordering information below).
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IKKα Antibody (C-6) is a mouse monoclonal IgG1 antibody that detects IKKα in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). IKKα, also known as CHUK, plays a pivotal role in the activation of the transcription factor NFκB, which is crucial for regulating immune responses and inflammation. Located primarily in the cytoplasm, IKKα is part of a multi-subunit complex that includes IKKβ and IKKγ (NEMO), and phosphorylates the inhibitory protein IκB on specific serine residues. This phosphorylation event leads to IκB degradation, allowing NFκB to translocate to the nucleus and initiate the transcription of target genes involved in inflammatory responses. The significance of IKKα in this signaling pathway highlights anti-IKKα antibody (C-6) as a valuable tool for studying chronic inflammation, autoimmune disorders, and cancer. Through facilitating IκB phosphorylation, IKKα maintains proper regulation of NFκB activity, making IKKα (C-6) antibody essential for investigating these critical biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IKK alpha Antibody (C-6) | sc-166231 | 200 µg/ml | $322.00 | |||
IKK alpha Antibody (C-6): m-IgG Fc BP-HRP Bundle | sc-540052 | 200 µg Ab; 10 µg BP | $361.00 | |||
IKK alpha Antibody (C-6): m-IgG1 BP-HRP Bundle | sc-541872 | 200 µg Ab; 20 µg BP | $361.00 |