Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
---|---|---|---|---|---|---|
Prostratin | 60857-08-1 | sc-203422 sc-203422A | 1 mg 5 mg | $138.00 $530.00 | 24 | |
Prostratin acts as an inhibitor of IκB kinase (IKK), engaging in specific interactions with the enzyme's active site. This binding modulates the phosphorylation of IκB proteins, thereby influencing the NF-κB signaling pathway. Prostratin's unique molecular structure allows it to stabilize the enzyme-substrate complex, affecting reaction kinetics and enhancing the selectivity of IKK inhibition. Its distinct conformational dynamics contribute to the regulation of cellular responses to stress and inflammation. |