IGFBP5 Antibody (G-7): sc-515184
- IGFBP5 Antibody (G-7) is a mouse monoclonal IgG2a κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 81-180 of IGFBP5 of human origin
- recommended for detection of precursor and mature IGFBP5 of mouse, rat and human origin by WB, IP, IF and ELISA
- available conjugated to HRP for WB, IHC(P) and ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for IGFBP5 Antibody (G-7) for WB applications. These reagents are now offered in bundles with IGFBP5 Antibody (G-7) (see ordering information below).
IGFBP5 Antibody (G-7) is a mouse monoclonal IgG2a antibody that detects Insulin-like Growth Factor Binding Protein 5 (IGFBP5) in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IGFBP5 plays a crucial role in regulating the bioavailability of insulin-like growth factors (IGFs), which are essential for various cellular processes, including growth, differentiation, and survival. IGFBP5 is primarily secreted by myoblasts and is believed to be instrumental in muscle differentiation, highlighting its importance in muscle development and repair. Additionally, IGFBP5 can modulate the actions of IGFs independently, suggesting distinct biological functions beyond its role as a binding protein. IGFBP5′s ability to interact with other proteins and influence signaling pathways makes IGFBP5 a significant player in the complex network of growth factor regulation. anti-IGFBP5 antibody (G-7) serves as an invaluable tool for researchers studying growth factor signaling and muscle biology.
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IGFBP5 Antibody (G-7) References:
- Insulin-like growth factor-binding protein 5 (Igfbp5) compromises survival, growth, muscle development, and fertility in mice. | Salih, DA., et al. 2004. Proc Natl Acad Sci U S A. 101: 4314-9. PMID: 15010534
- Multifunctional roles of insulin-like growth factor binding protein 5 in breast cancer. | Akkiprik, M., et al. 2008. Breast Cancer Res. 10: 212. PMID: 18710598
- Role of insulin-like growth factor-binding protein 5 (IGFBP5) in organismal and pancreatic beta-cell growth. | Gleason, CE., et al. 2010. Mol Endocrinol. 24: 178-92. PMID: 19897600
- The Wilms tumor protein WT1 stimulates transcription of the gene encoding insulin-like growth factor binding protein 5 (IGFBP5). | Müller, M., et al. 2017. Gene. 619: 21-29. PMID: 28366834
- Expression of Insulin-Like Growth Factor Binding Protein-5 (IGFBP5) Reverses Cisplatin-Resistance in Esophageal Carcinoma. | Chan, D., et al. 2018. Cells. 7: PMID: 30241323
- Insulin-Like Growth Factor Binding Protein 5-A Probable Target of Kidney Renal Papillary Renal Cell Carcinoma. | Wang, S., et al. 2019. Biomed Res Int. 2019: 3210324. PMID: 31886201
- Antimicrobial peptide derived from insulin-like growth factor-binding protein 5 improves diabetic wound healing. | Yue, H., et al. 2022. Wound Repair Regen. 30: 232-244. PMID: 35092133
- CCCTC-Binding Factor Mediates the Transcription of Insulin-Like Growth Factor Binding Protein 5 Through EZH2 in Ulcerative Colitis. | Gu, D., et al. 2023. Dig Dis Sci. 68: 778-790. PMID: 35705732
- Secreted insulin-like growth factor binding protein 5 functions as a tumor suppressor and chemosensitizer through inhibiting insulin-like growth factor 1 receptor/protein kinase B pathway in acute myeloid leukemia. | Zhang, B., et al. 2024. Neoplasia. 47: 100952. PMID: 38159363
- Serum insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5 levels in aging and age-associated diseases. | Mohan, S. and Baylink, DJ. 1997. Endocrine. 7: 87-91. PMID: 9449039
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IGFBP5 Antibody (G-7) | sc-515184 | 200 µg/ml | $316.00 | |||
IGFBP5 Antibody (G-7): m-IgG Fc BP-HRP Bundle | sc-538756 | 200 µg Ab; 10 µg BP | $354.00 | |||
IGFBP5 Antibody (G-7): m-IgGκ BP-HRP Bundle | sc-536424 | 200 µg Ab; 40 µg BP | $354.00 | |||
IGFBP5 Antibody (G-7): m-IgG2a BP-HRP Bundle | sc-548396 | 200 µg Ab; 10 µg BP | $354.00 | |||
IGFBP5 Antibody (G-7) HRP | sc-515184 HRP | 200 µg/ml | $316.00 |