Ig λ chain Antibody (N10/2): sc-53344

Ig λ chain Antibody (N10/2) is a mouse monoclonal IgG1 antibody that detects the Ig lambda chain protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Ig λ chain (N10/2) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. The Ig lambda chain plays a crucial role in the immune response, as one of the two types of light chains that can pair with heavy chains to form functional antibodies. These antibodies are essential for recognizing and neutralizing foreign antigens, thus facilitating the immune system′s ability to protect the body from infections and diseases. The structure of immunoglobulins, which consists of two identical heavy chains and two identical light chains linked by disulfide bonds, allows for a diverse range of antigen recognition due to the variable regions formed by the rearrangement of gene segments. This structural diversity is vital for the adaptive immune response, enabling the body to respond effectively to a wide array of pathogens. The unique genetic recombination process that generates the variable regions of the light chains, including both kappa and lambda types, ensures that individual B cells express only one type of light chain, which is critical for maintaining the specificity and efficacy of the antibody response.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Ig λ chain Antibody (N10/2) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-Ig λ chain Antibody (N10/2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Ig λ chain Antibody (N10/2) Specifications

Alternate Product Name: Ig λ chain

Product Clone Name: N10/2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: Ig λ chain

Epitope Species: human

Product Reactivity/Detection: Ig λ chain

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P)

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for Ig λ chain Antibody (N10/2): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin