IFT172 Antibody (A-11): sc-398393
- IFT172 Antibody (A-11) is a mouse monoclonal IgG1 κ IFT172 antibody, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 1353-1652 mapping within an internal region of IFT172 of human origin
- IFT172 Antibody (A-11) is recommended for detection of IFT172 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-IFT172 Antibody (A-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for IFT172 Antibody (A-11) for WB applications. These reagents are now offered in bundles with IFT172 Antibody (A-11) (see ordering information below).
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IFT172 Antibody (A-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects IFT172 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IFT172 (A-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. IFT172, also known as intraflagellar transport 172, plays a crucial role in cilia assembly and maintenance, which are essential for numerous cellular processes, including signaling pathways such as the hedgehog pathway. Cilia are involved in regulating various developmental processes and cellular signaling, making proper functioning of IFT172 vital for normal cellular activity. IFT172 localizes to the cilium as part of the intraflagellar transport machinery, facilitating transport of proteins necessary for ciliary structure and function. IFT172 contains fourteen tetratricopeptide repeats and nine WD repeats, which enable interactions with other intraflagellar transport proteins. Disruption of IFT172 function can lead to defects in cilia formation and maintenance, resulting in various developmental disorders and diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
IFT172 Antibody (A-11) References:
- Identification of a conserved protein that interacts with specific LIM homeodomain transcription factors. | Howard, PW. and Maurer, RA. 2000. J Biol Chem. 275: 13336-42. PMID: 10788441
- Localization of intraflagellar transport protein IFT52 identifies basal body transitional fibers as the docking site for IFT particles. | Deane, JA., et al. 2001. Curr Biol. 11: 1586-90. PMID: 11676918
- IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia. | Baker, SA., et al. 2003. J Biol Chem. 278: 34211-8. PMID: 12821668
- Hedgehog signalling in the mouse requires intraflagellar transport proteins. | Huangfu, D., et al. 2003. Nature. 426: 83-7. PMID: 14603322
- Intraflagellar transport genes are essential for differentiation and survival of vertebrate sensory neurons. | Tsujikawa, M. and Malicki, J. 2004. Neuron. 42: 703-16. PMID: 15182712
- Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors. | Liu, A., et al. 2005. Development. 132: 3103-11. PMID: 15930098
- Characterization of the intraflagellar transport complex B core: direct interaction of the IFT81 and IFT74/72 subunits. | Lucker, BF., et al. 2005. J Biol Chem. 280: 27688-96. PMID: 15955805
- Spatial distribution of intraflagellar transport proteins in vertebrate photoreceptors. | Luby-Phelps, K., et al. 2008. Vision Res. 48: 413-23. PMID: 17931679
- Intraflagellar transport and functional analysis of genes required for flagellum formation in trypanosomes. | Absalon, S., et al. 2008. Mol Biol Cell. 19: 929-44. PMID: 18094047
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IFT172 Antibody (A-11) | sc-398393 | 200 µg/ml | $316.00 | |||
IFT172 Antibody (A-11): m-IgG Fc BP-HRP Bundle | sc-530782 | 200 µg Ab; 10 µg BP | $354.00 | |||
IFT172 Antibody (A-11): m-IgGκ BP-HRP Bundle | sc-524323 | 200 µg Ab, 40 µg BP | $354.00 | |||
IFT172 Antibody (A-11): m-IgG1 BP-HRP Bundle | sc-544250 | 200 µg Ab; 20 µg BP | $354.00 | |||
IFT172 Antibody (A-11) AC | sc-398393 AC | 500 µg/ml, 25% agarose | $416.00 | |||
IFT172 Antibody (A-11) HRP | sc-398393 HRP | 200 µg/ml | $316.00 | |||
IFT172 Antibody (A-11) FITC | sc-398393 FITC | 200 µg/ml | $330.00 | |||
IFT172 Antibody (A-11) PE | sc-398393 PE | 200 µg/ml | $343.00 | |||
IFT172 Antibody (A-11) Alexa Fluor® 488 | sc-398393 AF488 | 200 µg/ml | $357.00 | |||
IFT172 Antibody (A-11) Alexa Fluor® 546 | sc-398393 AF546 | 200 µg/ml | $357.00 | |||
IFT172 Antibody (A-11) Alexa Fluor® 594 | sc-398393 AF594 | 200 µg/ml | $357.00 | |||
IFT172 Antibody (A-11) Alexa Fluor® 647 | sc-398393 AF647 | 200 µg/ml | $357.00 | |||
IFT172 Antibody (A-11) Alexa Fluor® 680 | sc-398393 AF680 | 200 µg/ml | $357.00 | |||
IFT172 Antibody (A-11) Alexa Fluor® 790 | sc-398393 AF790 | 200 µg/ml | $357.00 |