IFN-γ/Interferon gamma Antibody (H3-1): sc-51975
- IFN-γ/Interferon gamma Antibody (H3-1) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against human recombinant interferon γ
- recommended for detection of IFNγ of human origin by WB and IP
- See IFN-γ/Interferon gamma (E-10): sc-373727 for IFN-γ/Interferon gamma antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IFN-γ/Interferon gamma Antibody (H3-1). This work is in progress.
IFN-γ Antibody (H3-1) is a mouse monoclonal IgG1 antibody that detects Interferon (IFN)-γ in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). IFN-γ plays a crucial role in the immune response, acting as an antiviral and antiparasitic agent produced by activated CD4+/CD8+ lymphocytes and natural killer cells. Anti-IFN-γ antibody (H3-1) recognizes a protein that modulates T cell growth and differentiation while inhibiting B cell proliferation, thereby shaping the adaptive immune response. IFN-γ′s active form is a homodimer, with each subunit comprising six helices, and this dimeric structure is stabilized by non-covalent interactions at the interface of the helices. The precursor of IFN-γ consists of 166 amino acids, which includes a 23 amino acid secretory sequence, and IFN-γ functionality is further enhanced by the presence of multiple forms resulting from variable glycosylation and the formation of dimers and tetramers under non-denaturing conditions. The versatility of IFN-γ in immune modulation underscores its significance in therapeutic applications and research, making IFN-γ monoclonal antibody (H3-1) an essential tool for studying immune responses in human samples.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IFN-γ/Interferon gamma Antibody (H3-1) | sc-51975 | 100 µg/ml | $316.00 |