IFN-γ/Interferon gamma Antibody (E8H1): sc-101424
- IFN-γ/Interferon gamma Antibody (E8H1) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against recombinant IFN-γ of human origin
- recommended for detection of IFN-γ of human origin by WB, IP and ELISA
- See IFN-γ/Interferon gamma (E-10): sc-373727 for IFN-γ/Interferon gamma antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IFN-γ/Interferon gamma Antibody (E8H1). This work is in progress.
IFN-γ Antibody (E8H1) is a mouse monoclonal IgG1 antibody that detects Interferon gamma (IFN-γ) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). IFN-γ plays a crucial role in the immune response, acting as a potent antiviral and antiparasitic agent produced by activated CD4+/CD8+ lymphocytes and natural killer cells. Anti-IFN-γ antibody (E8H1) recognizes a protein that modulates T cell growth and differentiation while inhibiting B cell proliferation, thereby orchestrating a balanced immune response. IFN-γ′s active form is a homodimer, with each subunit comprising six helices, and this dimeric structure is stabilized by non-covalent interactions at the interface of the helices, which is essential for biological activity. The IFN-γ precursor consists of 166 amino acids, including a 23 amino acid secretory sequence, and functionality is further influenced by post-translational modifications such as glycosylation, which can lead to multiple isoforms under non-denaturing conditions, including dimers and tetramers. IFN-γ monoclonal antibody (E8H1) serves as an invaluable tool for studying immune responses in human samples, given IFN-γ′s versatility in immune regulation and significance in therapeutic applications and research.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IFN-γ/Interferon gamma Antibody (E8H1) | sc-101424 | 200 µg/ml | $322.00 |