ICB1 Antibody (H-8): sc-515413
- ICB1 Antibody (H-8) is a mouse monoclonal IgG2a κ ICB1 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 218-240 within an internal region of ICB1 of human origin
- ICB1 Antibody (H-8) is recommended for detection of ICB1 isoforms 1, 3 and 5 of human origin by WB, IP, IF and ELISA
- Anti-ICB1 Antibody (H-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ICB1 Antibody (H-8) for WB applications. These reagents are now offered in bundles with ICB1 Antibody (H-8) (see ordering information below).
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ICB1 Antibody (H-8) is a mouse monoclonal IgG2a kappa light chain antibody that detects ICB1 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ICB1 (H-8) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. ICB1 protein plays a crucial role in cellular processes, particularly in the regulation of gene expression and cellular signaling pathways, which are vital for maintaining normal cellular function and responding to environmental stimuli. Understanding ICB1 function is important, as dysregulation has been implicated in various diseases, including cancer and neurodegenerative disorders. ICB1′s ability to interact with specific transcription factors and other signaling molecules highlights its significance in cellular communication and the potential consequences of malfunction. With broad applications and critical role in cellular biology, anti-ICB1 antibody (H-8) is an essential tool for researchers investigating the complexities of human health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ICB1 Antibody (H-8) References:
- Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family. | Blackwood, DH., et al. 2001. Am J Hum Genet. 69: 428-33. PMID: 11443544
- New insights into the evolution of chromosome 1. | Weise, A., et al. 2005. Cytogenet Genome Res. 108: 217-22. PMID: 15545733
- Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody. | McClintock, D., et al. 2006. Proc Natl Acad Sci U S A. 103: 2154-9. PMID: 16461887
- Cell biology: ageing nucleus gets out of shape. | Lans, H. and Hoeijmakers, JH. 2006. Nature. 440: 32-4. PMID: 16511477
- Chromosome 1 abnormalities in multiple myeloma. | Marzin, Y., et al. 2006. Anticancer Res. 26: 953-9. PMID: 16619492
- Lamin A-dependent nuclear defects in human aging. | Scaffidi, P. and Misteli, T. 2006. Science. 312: 1059-63. PMID: 16645051
- Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness. | Hennah, W., et al. 2006. Schizophr Bull. 32: 409-16. PMID: 16699061
- The DNA sequence and biological annotation of human chromosome 1. | Gregory, SG., et al. 2006. Nature. 441: 315-21. PMID: 16710414
- Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1. | Watson, ML., et al. 1990. J Exp Med. 172: 263-72. PMID: 1694218
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ICB1 Antibody (H-8) | sc-515413 | 200 µg/ml | $316.00 | |||
ICB1 Antibody (H-8): m-IgG Fc BP-HRP Bundle | sc-531357 | 200 µg Ab; 10 µg BP | $354.00 | |||
ICB1 Antibody (H-8): m-IgGκ BP-HRP Bundle | sc-525028 | 200 µg Ab, 40 µg BP | $354.00 | |||
ICB1 Antibody (H-8): m-IgG2a BP-HRP Bundle | sc-547771 | 200 µg Ab; 10 µg BP | $354.00 | |||
ICB1 Antibody (H-8) AC | sc-515413 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ICB1 Antibody (H-8) HRP | sc-515413 HRP | 200 µg/ml | $316.00 | |||
ICB1 Antibody (H-8) FITC | sc-515413 FITC | 200 µg/ml | $330.00 | |||
ICB1 Antibody (H-8) PE | sc-515413 PE | 200 µg/ml | $343.00 | |||
ICB1 Antibody (H-8) Alexa Fluor® 488 | sc-515413 AF488 | 200 µg/ml | $357.00 | |||
ICB1 Antibody (H-8) Alexa Fluor® 546 | sc-515413 AF546 | 200 µg/ml | $357.00 | |||
ICB1 Antibody (H-8) Alexa Fluor® 594 | sc-515413 AF594 | 200 µg/ml | $357.00 | |||
ICB1 Antibody (H-8) Alexa Fluor® 647 | sc-515413 AF647 | 200 µg/ml | $357.00 | |||
ICB1 Antibody (H-8) Alexa Fluor® 680 | sc-515413 AF680 | 200 µg/ml | $357.00 | |||
ICB1 Antibody (H-8) Alexa Fluor® 790 | sc-515413 AF790 | 200 µg/ml | $357.00 | |||
ICB1 (H-8) Neutralizing Peptide | sc-515413 P | 100 µg/0.5 ml | $68.00 |