HSV-1 ICP8 Antibody (11E2): sc-53330
- HSV-1 ICP8 Antibody (11E2) is a mouse monoclonal IgG1 κ HSV-1 ICP8 antibody, cited in 12 publications, provided at 200 µg/ml
- raised against ICP8 purified from U-35-VERO cells
- HSV-1 ICP8 Antibody (11E2) is recommended for detection of Herpes simplex virus by WB and IP
- Anti-HSV-1 ICP8 Antibody (11E2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for HSV-1 ICP8 Antibody (11E2) for WB applications. These reagents are now offered in bundles with HSV-1 ICP8 Antibody (11E2) (see ordering information below).
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SEE ALSO...
HSV-1 ICP8 Antibody (11E2) is a mouse monoclonal IgG1 kappa light chain antibody that detects HSV-1 ICP8 protein of Herpes simplex virus origin by western blotting (WB) and immunoprecipitation (IP). Anti-HSV-1 ICP8 antibody (11E2) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. The herpes simplex virus (HSV), commonly known for causing cold sores, is a highly contagious pathogen that can establish lifelong latent infections in the host. HSV-1 ICP8 plays a crucial role in the viral life cycle as the major single-strand DNA-binding protein, essential for viral genome replication. HSV-1 ICP8 facilitates the conversion of single-stranded DNA into a double-stranded form, which is vital for virus replication and propagation within the host. HSV-1 ICP8′s ability to destabilize DNA helices at higher concentrations assists in the reverse reaction, highlighting dual functionality in DNA metabolism. Understanding HSV-1 ICP8′s role is important for developing therapeutic strategies against herpes simplex virus infections, as targeting this protein could disrupt viral replication and mitigate disease progression.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HSV-1 ICP8 Antibody (11E2) | sc-53330 | 200 µg/ml | $322.00 | |||
HSV-1 ICP8 Antibody (11E2): m-IgG Fc BP-HRP Bundle | sc-528563 | 200 µg Ab; 10 µg BP | $361.00 | |||
HSV-1 ICP8 Antibody (11E2): m-IgGκ BP-HRP Bundle | sc-520969 | 200 µg Ab, 40 µg BP | $361.00 | |||
HSV-1 ICP8 Antibody (11E2) AC | sc-53330 AC | 500 µg/ml, 25% agarose | $424.00 | |||
HSV-1 ICP8 Antibody (11E2) HRP | sc-53330 HRP | 200 µg/ml | $322.00 | |||
HSV-1 ICP8 Antibody (11E2) FITC | sc-53330 FITC | 200 µg/ml | $336.00 | |||
HSV-1 ICP8 Antibody (11E2) PE | sc-53330 PE | 200 µg/ml | $349.00 | |||
HSV-1 ICP8 Antibody (11E2) Alexa Fluor® 488 | sc-53330 AF488 | 200 µg/ml | $364.00 | |||
HSV-1 ICP8 Antibody (11E2) Alexa Fluor® 546 | sc-53330 AF546 | 200 µg/ml | $364.00 | |||
HSV-1 ICP8 Antibody (11E2) Alexa Fluor® 594 | sc-53330 AF594 | 200 µg/ml | $364.00 | |||
HSV-1 ICP8 Antibody (11E2) Alexa Fluor® 647 | sc-53330 AF647 | 200 µg/ml | $364.00 | |||
HSV-1 ICP8 Antibody (11E2) Alexa Fluor® 680 | sc-53330 AF680 | 200 µg/ml | $364.00 | |||
HSV-1 ICP8 Antibody (11E2) Alexa Fluor® 790 | sc-53330 AF790 | 200 µg/ml | $364.00 |