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HSPA12B Antibody (A-12) is a mouse monoclonal IgG1 antibody that detects HSPA12B in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HSPA12B, a 686 amino acid protein, is predominantly expressed in the endothelial cells of muscle and heart tissues, as well as in the liver and kidney, highlighting its critical role in various physiological processes. HSPA12B is a member of the heat shock protein 70 family, characterized by the presence of a heat shock protein 70 ATPase domain, which is essential for its function as a molecular chaperone. HSPA12B plays a crucial role in angiogenesis and is involved in the cellular stress response, especially during wound healing. Notably, HSPA12B shows increased expression in atherosclerotic lesions, indicating a potential role in atherogenesis. This elevated expression may serve a protective function, correlating with higher levels of HSP 70 and suggesting HSPA12B′s participation in cellular defense against atherosclerotic damage. Anti-HSPA12B antibody (A-12) enables researchers to gain valuable insights into HSPA12B′s involvement in stress signaling and implications in cardiovascular health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HSPA12B Antibody (A-12) | sc-376020 | 200 µg/ml | $322.00 | |||
HSPA12B Antibody (A-12): m-IgG Fc BP-HRP Bundle | sc-540497 | 200 µg Ab; 10 µg BP | $361.00 | |||
HSPA12B Antibody (A-12): m-IgG1 BP-HRP Bundle | sc-542160 | 200 µg Ab; 20 µg BP | $361.00 | |||
HSPA12B (A-12) Neutralizing Peptide | sc-376020 P | 100 µg/0.5 ml | $69.00 |