HSP 60 Antibody (F-9) is a mouse monoclonal IgG2a antibody that detects HSP 60 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). HSP 60, a member of the heat shock protein family, plays a crucial role as a molecular chaperone, primarily located in the mitochondria, where HSP 60 assists in the proper folding and assembly of newly synthesized proteins destined for the mitochondrial matrix. This localization is vital because mitochondrial dysfunction can lead to a range of diseases, including neurodegenerative disorders and metabolic syndromes. By ensuring that proteins are correctly folded and functional, HSP 60 helps maintain cellular homeostasis and protects against stress-induced damage. Additionally, HSP 60 has been implicated in immune responses, acting as a cell surface marker for γ/δ T cell recognition, which highlights HSP 60′s importance not only in cellular function but also in the immune system. Anti-HSP 60 antibody (F-9) is an essential tool for researchers studying mitochondrial biology, protein folding mechanisms, and immune interactions.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HSP 60 Antibody (F-9) | sc-376261 | 200 µg/ml | $316.00 | |||
HSP 60 Antibody (F-9): m-IgG Fc BP-HRP Bundle | sc-540537 | 200 µg Ab; 10 µg BP | $354.00 | |||
HSP 60 Antibody (F-9): m-IgG2a BP-HRP Bundle | sc-546920 | 200 µg Ab; 10 µg BP | $354.00 | |||
HSP 60 (F-9) Neutralizing Peptide | sc-376261 P | 100 µg/0.5 ml | $68.00 |