HSP 60 Antibody (24): sc-136291
- HSP 60 Antibody (24) is a mouse monoclonal IgG1 κ, cited in 12 publications, provided at 200 µg/ml
- raised against amino acids 1-200 of HSP 60 of human origin
- Anti-HSP 60 Antibody (24) is recommended for detection of HSP60 of mouse, rat and human origin by WB, IP and IF
- See HSP 60 (LK1): sc-59567 for HSP 60 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for HSP 60 Antibody (24) for WB applications. This reagent is now offered in a bundle with HSP 60 Antibody (24) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
HSP 60 Antibody (24) is a mouse monoclonal IgG1 antibody that detects HSP 60 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). HSP 60, a member of the heat shock protein family, plays a crucial role as a molecular chaperone, primarily located in the mitochondria, where anti-HSP 60 antibody (24) assists in the proper folding and assembly of newly synthesized proteins destined for the mitochondrial matrix. This localization is vital because HSP 60 ensures proteins are correctly folded to maintain mitochondrial function, which is essential for energy production and cellular metabolism. Additionally, HSP 60 is involved in the assembly of multiprotein complexes and can also act as a cell surface marker for γ/δ T cell recognition, highlighting HSP 60′s importance in both cellular stress responses and immune system interactions. HSP 60 monoclonal antibody (24) provides a reliable tool for researchers studying mitochondrial function, protein folding mechanisms, and immune responses, making HSP 60 (24) antibody an invaluable asset in cellular and molecular biology.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
HSP 60 Antibody (24) References:
- Macrophage L-type Ca2+ channel antagonists alter Chlamydia pneumoniae MOMP and HSP-60 mRNA gene expression, and improve antibiotic susceptibility. | Azenabor, AA., et al. 2003. Immunobiology. 207: 237-45. PMID: 12952346
- Peptide recognition, T cell receptor usage and HLA restriction elements of human heat-shock protein (hsp) 60 and mycobacterial 65-kDa hsp-reactive T cell clones from rheumatoid synovial fluid. | Quayle, AJ., et al. 1992. Eur J Immunol. 22: 1315-22. PMID: 1577070
- Comparative immunolocalization of heat shock proteins (Hsp)-60, -70, -90 in boar, stallion, dog and cat spermatozoa. | Volpe, S., et al. 2008. Reprod Domest Anim. 43: 385-92. PMID: 18226022
- The effect of balneotherapy on C-reactive protein, serum cholesterol, triglyceride, total antioxidant status and HSP-60 levels. | Oláh, M., et al. 2010. Int J Biometeorol. 54: 249-54. PMID: 19937457
- Concentration of circulating autoantibodies against HSP 60 is lowered through diving when compared to non-diving rats. | Havnes, MB., et al. 2012. Microb Ecol Health Dis. 23: PMID: 23990832
- Himatanthus drasticus (Apocynaceae) latex reduces oxidative stress and modulates CD4+, CD8+, FoxP3+ and HSP-60+ expressions in Sarcoma 180-bearing mice. | Santos, GJL., et al. 2018. J Ethnopharmacol. 220: 159-168. PMID: 29079220
- Seropositivity for the human heat shock protein (Hsp)60 accompanying seropositivity for Chlamydia trachomatis is less prevalent among tubal ectopic pregnancy cases than individuals with normal reproductive history. | Ozyurek, ES., et al. 2018. Eur J Obstet Gynecol Reprod Biol. 223: 119-122. PMID: 29518642
- The abundance and localization of heat shock proteins (HSP)-60, -70, and -90 in the oviductal ampulla of hamadryas baboon (Papio hamadryas) during the menstrual cycle. | Albrizio, M., et al. 2024. Vet Res Commun. 48: 979-990. PMID: 38038815
- Response of a murine epidermal V gamma 1/V delta 6-TCR+ hybridoma to heat shock protein HSP-60. | Reardon, CL., et al. 1994. J Invest Dermatol. 103: 544-6. PMID: 7930679
- Interaction of HSP 60 with proteins imported into the mitochondrial matrix. | Rospert, S. and Hallberg, R. 1995. Methods Enzymol. 260: 287-92. PMID: 8592452
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HSP 60 Antibody (24) | sc-136291 | 200 µg/ml | $322.00 | |||
HSP 60 Antibody (24): m-IgGκ BP-HRP Bundle | sc-521352 | 200 µg Ab, 40 µg BP | $361.00 |