



HoxD9 Antibody (E-3) is a mouse monoclonal IgG1 antibody that detects HoxD9 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HoxD9 is a crucial transcription factor involved in the regulation of embryonic development and cellular differentiation, primarily by modulating downstream target genes. HoxD9 expression is particularly significant during the early stages of joint development in mice, where HoxD9 is localized in the articular cartilage, highlighting HoxD9′s role in skeletal formation. Notably, HoxD9 is also implicated in pathological conditions, as HoxD9 is expressed in the synovial tissue of arthritic mice, suggesting a potential involvement in the inflammatory processes associated with arthritis. In patients with rheumatoid arthritis, HoxD9 is highly expressed in synoviocytes, contrasting with HoxD9′s absence in osteoarthritis cases, which may indicate a specific role in RA pathology. Furthermore, the differential expression of HoxD9 in the human cervical cancer cell line HeLa, compared to normal cervical tissue, points to HoxD9′s potential involvement in tumorigenesis. The multifaceted nature of HoxD9, including HoxD9′s interaction with various regulatory elements and cofactors, underscores HoxD9′s importance in both normal physiological processes and disease states, making anti-HoxD9 antibody (E-3) an essential tool for researchers studying these critical biological pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HoxD9 Antibody (E-3) | sc-137038 | 200 µg/ml | $322.00 | |||
HoxD9 Antibody (E-3): m-IgG Fc BP-HRP Bundle | sc-539920 | 200 µg Ab; 10 µg BP | $361.00 | |||
HoxD9 Antibody (E-3): m-IgG1 BP-HRP Bundle | sc-541788 | 200 µg Ab; 20 µg BP | $361.00 | |||
HoxD9 Antibody (E-3) X | sc-137038 X | 200 µg/0.1 ml | $322.00 |