HOOK3 Antibody (C-10): sc-398924
- HOOK3 Antibody (C-10) is a mouse monoclonal IgG2a κ HOOK3 antibody, cited in 4 publications, provided at 200 µg/ml
- raised against amino acids 202-253 mapping within an internal region of HOOK3 of human origin
- HOOK3 Antibody (C-10) is recommended for detection of HOOK3 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-HOOK3 Antibody (C-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for HOOK3 Antibody (C-10) for WB applications. These reagents are now offered in bundles with HOOK3 Antibody (C-10) (see ordering information below).
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HOOK3 Antibody (C-10) is a mouse monoclonal IgG2a kappa light chain antibody that detects HOOK3 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HOOK3 (C-10) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. HOOK3 protein plays a crucial role in the organization of the cis-Golgi compartment, which is essential for proper protein sorting and trafficking within the cell. By facilitating the interaction between microtubules and organelles, HOOK3 ensures that proteins are accurately delivered to their destinations, thereby maintaining cellular function and homeostasis. HOOK3 exists as a homodimer, likely formed through its central coiled-coil domain, which is significant for its structural integrity and functional interactions. HOOK3′s ability to bind to microtubules and organelles underscores its importance in the dynamic processes of intracellular transport, making anti-HOOK3 antibody (C-10) a valuable tool for researchers studying cellular organization and trafficking mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
HOOK3 Antibody (C-10) References:
- The Golgi-associated hook3 protein is a member of a novel family of microtubule-binding proteins. | Walenta, JH., et al. 2001. J Cell Biol. 152: 923-34. PMID: 11238449
- The Salmonella SpiC protein targets the mammalian Hook3 protein function to alter cellular trafficking. | Shotland, Y., et al. 2003. Mol Microbiol. 49: 1565-76. PMID: 12950921
- IIGP, a member of the IFN inducible and microbial defense mediating 47 kDa GTPase family, interacts with the microtubule binding protein hook3. | Kaiser, F., et al. 2004. J Cell Sci. 117: 1747-56. PMID: 15075236
- The microtubule-binding protein Hook3 interacts with a cytoplasmic domain of scavenger receptor A. | Sano, H., et al. 2007. J Biol Chem. 282: 7973-81. PMID: 17237231
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HOOK3 Antibody (C-10) | sc-398924 | 200 µg/ml | $322.00 | |||
HOOK3 Antibody (C-10): m-IgG Fc BP-HRP Bundle | sc-530974 | 200 µg Ab; 10 µg BP | $361.00 | |||
HOOK3 Antibody (C-10): m-IgGκ BP-HRP Bundle | sc-524541 | 200 µg Ab, 40 µg BP | $361.00 | |||
HOOK3 Antibody (C-10): m-IgG2a BP-HRP Bundle | sc-547649 | 200 µg Ab; 10 µg BP | $361.00 | |||
HOOK3 Antibody (C-10) AC | sc-398924 AC | 500 µg/ml, 25% agarose | $424.00 | |||
HOOK3 Antibody (C-10) HRP | sc-398924 HRP | 200 µg/ml | $322.00 | |||
HOOK3 Antibody (C-10) FITC | sc-398924 FITC | 200 µg/ml | $336.00 | |||
HOOK3 Antibody (C-10) PE | sc-398924 PE | 200 µg/ml | $349.00 | |||
HOOK3 Antibody (C-10) Alexa Fluor® 488 | sc-398924 AF488 | 200 µg/ml | $364.00 | |||
HOOK3 Antibody (C-10) Alexa Fluor® 546 | sc-398924 AF546 | 200 µg/ml | $364.00 | |||
HOOK3 Antibody (C-10) Alexa Fluor® 594 | sc-398924 AF594 | 200 µg/ml | $364.00 | |||
HOOK3 Antibody (C-10) Alexa Fluor® 647 | sc-398924 AF647 | 200 µg/ml | $364.00 | |||
HOOK3 Antibody (C-10) Alexa Fluor® 680 | sc-398924 AF680 | 200 µg/ml | $364.00 | |||
HOOK3 Antibody (C-10) Alexa Fluor® 790 | sc-398924 AF790 | 200 µg/ml | $364.00 |