HNF-3β Antibody (H-8): sc-271104
- HNF-3β Antibody (H-8) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 261-370 mapping within an internal region of HNF-3β of human origin
- recommended for detection of HNF-3β of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for Gel Supershift and ChIP applications (sc-271104 X, 200 µg/0.1 ml)
- See HNF-3β (H-4): sc-374376 for HNF-3β antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for HNF-3β Antibody (H-8) for WB applications. This reagent is now offered in a bundle with HNF-3β Antibody (H-8) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
HNF-3β Antibody (H-8) is a mouse monoclonal IgG2b kappa light chain antibody raised against amino acids 261-370 mapping within an internal region of HNF-3β of human origin, exhibiting reactivity with mouse, rat, and human proteins in applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HNF-3β, also known as FOXA2 (Forkhead Box A2), is a transcription factor crucial for regulating gene expression during embryonic development and in adult tissues. Structurally, HNF-3β features a conserved forkhead or winged-helix DNA-binding domain, characterized by a helix-turn-helix motif flanked by two wing-like loops, which allows HNF-3β to bind specific DNA sequences effectively. This structural configuration is essential because HNF-3β functions as a pioneer transcription factor, capable of accessing compacted chromatin and facilitating the recruitment of other transcription factors to regulate genes involved in vital processes like metabolism, organ development, and cell differentiation. The ability of HNF-3β to modulate chromatin structure and influence gene accessibility underscores its importance in developmental biology and disease research, making anti-HNF-3β antibody (H-8) a valuable tool for scientists investigating pathways related to liver and pancreas development, as well as disorders stemming from its dysregulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HNF-3β Antibody (H-8) | sc-271104 | 200 µg/ml | $316.00 | |||
HNF-3β Antibody (H-8): m-IgGκ BP-HRP Bundle | sc-534869 | 200 µg Ab; 40 µg BP | $354.00 | |||
HNF-3β Antibody (H-8) X | sc-271104 X | 200 µg/0.1 ml | $316.00 |