HLA-DR Antibody (LN3): sc-59252

HLA-DR Antibody (LN3) is a mouse monoclonal IgG2b kappa light chain antibody, designed to target the HLA-DR protein, also known as the Major Histocompatibility Complex class II (MHC II) cell surface receptor. HLA-DR plays a critical role in the immune system by presenting processed antigenic peptides to CD4+ helper T cells, thereby initiating and regulating immune responses. This function is essential for the body′s ability to recognize and defend against pathogens, as well as in the development of immune tolerance. Anti-HLA-DR antibody (LN3) is raised against activated peripheral blood mononuclear cells of human origin. HLA-DR (LN3) antibody is recommended for use in various applications, including western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM), demonstrating robust reactivity with human HLA-DR. Understanding and targeting HLA-DR is crucial in research areas such as autoimmune diseases, transplantation, and immunotherapy, where modulation of immune responses is necessary. Anti-HLA-DR antibody (LN3) enables researchers to effectively study the expression and function of HLA-DR, contributing to advancements in immunological studies and therapeutic developments.

The preferred HLA-DR antibody is HLA-DR Antibody (L243): sc-18875.