HLA-A Antibody (C-6): sc-365485
- HLA-A Antibody (C-6) is a mouse monoclonal IgG2b κ, cited in 9 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 61-93 within an internal region of HLA-A of human origin
- recommended for detection of a broad range of HLA antigens of human origin by WB, IP, IF, IHC(P) and ELISA
- See MHC class I (W6/32): sc-32235 for HLA-A antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG2b BP-HRP is the preferred secondary detection reagent for HLA-A Antibody (C-6) for WB and IHC(P) applications. This reagent is now offered in a bundle with HLA-A Antibody (C-6) (see ordering information below).
HLA-A Antibody (C-6) is a mouse monoclonal IgG2b antibody that detects HLA-A in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). HLA-A plays a crucial role in the immune response by presenting peptide antigens to T lymphocytes, which is essential for the activation of adaptive immunity. Located on the surface of nearly all nucleated cells, HLA-A molecules are vital for the recognition of infected or malignant cells by cytotoxic T cells, thereby facilitating the elimination of these cells from the body. The structure of HLA-A consists of a membrane-anchored heavy chain that forms a heterodimer with beta-2-microglobulin, allowing for presentation of peptides derived from intracellular proteins. The polymorphic nature of HLA-A, with hundreds of alleles identified, contributes to the diversity of immune responses among individuals, making HLA-A a key factor in transplantation compatibility and susceptibility to autoimmune diseases. Anti-HLA-A antibody (C-6) serves as an invaluable tool for researchers studying immune responses, disease mechanisms, and therapeutic interventions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HLA-A Antibody (C-6) | sc-365485 | 200 µg/ml | $322.00 | |||
HLA-A Antibody (C-6): m-IgG2b BP-HRP Bundle | sc-548556 | 200 µg Ab; 10 µg BP | $361.00 | |||
HLA-A (C-6) Neutralizing Peptide | sc-365485 P | 100 µg/0.5 ml | $69.00 |