HIV-1 p24 Antibody (24-3): sc-69727
- HIV-1 p24 Antibody (24-3) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against HIV-1 p24 Gag
- recommended for detection of Gag p24 of HIV-1 origin by WB, IP and IF
- See HIV-1 p24 (24-4): sc-69728 for HIV-1 p24 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for HIV-1 p24 Antibody (24-3) for WB applications. This reagent is now offered in a bundle with HIV-1 p24 Antibody (24-3) (see ordering information below).
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HIV-1 p24 Antibody (24-3) is a mouse monoclonal IgG1 antibody that detects HIV-1 p24 specifically in HIV-1 by applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). HIV-1 p24 is a crucial viral protein encoded by the gag gene, playing a vital role in the structural integrity of the virus. Anti-HIV-1 p24 antibody (24-3) targets the viral capsid, which is essential for protecting the viral RNA and enzymes during the infection process. The capsid′s stability is critical for the virus′s ability to infect host cells and evade the immune response, making p24 a key target for both diagnostic and therapeutic strategies against HIV. HIV-1 p24 monoclonal antibody (24-3) enables researchers to effectively study the presence and quantity of this protein, aiding in the understanding of HIV pathogenesis and the development of antiviral therapies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
HIV-1 p24 Antibody (24-3) References:
- Transmission of HIV type 1 through blood transfusion from an antibody-negative/p24 antigen-negative donor. | Toro, C., et al. 2003. AIDS Res Hum Retroviruses. 19: 447-8. PMID: 12882652
- Viral growth assay to evaluate the replicative capacity of HIV-1 isolates. | Nicastri, E., et al. 2004. J Virol Methods. 115: 199-205. PMID: 14667536
- Genetic and biological properties of HIV type 1 isolates prevalent in villagers of the Cameroon equatorial rain forests and grass fields: further evidence of broad HIV type 1 genetic diversity. | Zhong, P., et al. 2003. AIDS Res Hum Retroviruses. 19: 1167-78. PMID: 14717120
- In vitro susceptibility of Thai seronegative donor CD8+ T lymphocytes to human immunodeficiency virus-1 (HIV-1) infection. | Haponsaph, R., et al. 2004. Asian Pac J Allergy Immunol. 22: 39-48. PMID: 15366657
- [Comparative evaluation of Hebei HIV-1 p24 kit for the detection of human immunodeficiency virus]. | Yang, YS., et al. 2007. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 21: 8-10. PMID: 17429521
- Evaluation of the ultrasensitive human immunodeficiency virus type 1 (HIV-1) p24 antigen assay performed on dried blood spots for diagnosis of HIV-1 infection in infants. | Patton, JC., et al. 2008. Clin Vaccine Immunol. 15: 388-91. PMID: 18057183
- Discovery of a Branched Peptide That Recognizes the Rev Response Element (RRE) RNA and Blocks HIV-1 Replication. | Dai, Y., et al. 2018. J Med Chem. 61: 9611-9620. PMID: 30289719
- Detection of human immunodeficiency virus type 1 p24 antigen and plasma RNA: relevance to indeterminate serologic tests. | Henrard, DR., et al. 1994. Transfusion. 34: 376-80. PMID: 8191559
- The acute retroviral syndrome and the pathogenesis of HIV-1 infection. | Clark, SJ. and Shaw, GM. 1993. Semin Immunol. 5: 149-55. PMID: 8347840
- Molecular inhibition of HIV type 1 by HIV type 2: effectiveness in peripheral blood mononuclear cells. | Al-Harthi, L., et al. 1998. AIDS Res Hum Retroviruses. 14: 59-64. PMID: 9453252
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
HIV-1 p24 Antibody (24-3) | sc-69727 | 200 µg/ml | $316.00 | |||
HIV-1 p24 Antibody (24-3): m-IgG Fc BP-HRP Bundle | sc-539231 | 200 µg Ab; 10 µg BP | $354.00 |