HIV-1 gp120 Antibody (A00019.01): sc-81010

HIV-1 gp120 Antibody (A00019.01) is a mouse monoclonal IgG1 kappa light chain antibody that detects HIV-1 gp120 protein of HIV-1 origin by enzyme-linked immunosorbent assay (ELISA). Anti-HIV-1 gp120 antibody (A00019.01) is available as the non-conjugated format. HIV-1 gp120 plays a crucial role in the viral life cycle, being responsible for initial attachment to host cells by binding to CD4 receptor on helper T cells. This interaction is vital for viral entry and serves as a target for neutralizing antibodies, making HIV-1 gp120 a key focus in HIV vaccine development. HIV-1 gp120′s structure, characterized by variable loops and conserved regions, evades host immune response while facilitating fusion of viral and cellular membranes through association with gp41. Understanding HIV-1 gp120′s structural dynamics remains essential for designing effective therapeutic strategies and vaccines against HIV-1, as these dynamics directly influence viral ability to infect host cells and establish infection.

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HIV-1 gp120 Antibody (A00019.01) References:

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The preferred HIV-1 gp120 antibody is HIV-1 gp120 Antibody (HIV1gp120): sc-57810.