Heme Oxygenase 1/HMOX1 Antibody (F-4): sc-390991

Heme Oxygenase 1 Antibody (F-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects Heme Oxygenase 1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-Heme Oxygenase 1 antibody (F-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Heme Oxygenase 1 (HO-1) plays a crucial role in cellular defense mechanisms by catalyzing the degradation of heme into biliverdin, carbon monoxide, and free iron, providing antioxidant protection and regulating inflammation. Carbon monoxide production by HO-1 acts as a signaling molecule that modulates various physiological processes, including vasodilation and neurotransmission. HO-1 is highly inducible in response to stressors such as oxidative stress, heavy metals, and inflammatory cytokines, making HO-1 a key player in the body′s adaptive response to injury and disease. In contrast, Heme Oxygenase 2 is constitutively expressed in the brain and produces carbon monoxide, which functions as a neurotransmitter, highlighting HO-1′s importance in both protective and regulatory roles within the cellular environment.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Heme Oxygenase 1/HMOX1 Antibody (F-4) has 105 citations in a variety of scientific publications.

Primary antibodies like Anti-Heme Oxygenase 1/HMOX1 Antibody (F-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Heme Oxygenase 1/HMOX1 Antibody (F-4) Specifications

Alternate Product Name: Heme Oxygenase 1

Product Clone Name: F-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 245-283

Epitope Target: Heme Oxygenase 1

Epitope Species: human

Product Reactivity/Detection: Heme Oxygenase 1

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: canine and bovine

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 105 citations in various scientific publications

Available Conjugates/Forms for Heme Oxygenase 1/HMOX1 Antibody (F-4): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin

The preferred Heme Oxygenase 1/HMOX1 antibody is Heme Oxygenase 1/HMOX1 Antibody (A-3): sc-136960.