Histone Deacetylase 3 (HDAC3) Antibody (3G6): sc-81600
- Histone Deacetylase 3 (HDAC3) Antibody (3G6) is a mouse monoclonal IgG2a κ, cited in 5 publications, provided at 200 µg/ml
- raised against amino acids 411-428 corresponding to the C-terminus of HDAC3 of human origin
- recommended for detection of HDAC3 of mouse, rat and human origin by WB, IP, IF and IHC(P)
- See Histone Deacetylase 3 (HDAC3) (A-3): sc-376957 for Histone Deacetylase 3 (HDAC3) antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Histone Deacetylase 3 (HDAC3) Antibody (3G6) for WB and IHC(P) applications. This reagent is now offered in a bundle with Histone Deacetylase 3 (HDAC3) Antibody (3G6) (see ordering information below).
HDAC3 Antibody (3G6) is a mouse monoclonal IgG2a antibody that detects HDAC3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. HDAC3, or Histone Deacetylase 3, plays a crucial role in the regulation of gene expression by removing acetyl groups from histones, leading to chromatin condensation and transcriptional repression. This function is vital for maintaining cellular homeostasis and regulating various biological processes, including cell differentiation, proliferation, and apoptosis. Dysregulation of HDAC3 has been implicated in several diseases, including cancer, where HDAC3 can contribute to the silencing of tumor suppressor genes. HDAC3 is predominantly located in the nucleus, where HDAC3 interacts with various transcription factors and co-repressors, thereby influencing the transcriptional landscape of the cell. Additionally, HDAC3 undergoes post-translational modifications, such as phosphorylation and ubiquitination, which can affect stability and activity, further underscoring HDAC3′s importance in cellular regulation. Anti-HDAC3 antibody (3G6) is an essential tool for researchers studying the intricate mechanisms of gene regulation and the role of histone deacetylases in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Histone Deacetylase 3 (HDAC3) Antibody (3G6) | sc-81600 | 200 µg/ml | $322.00 | |||
Histone Deacetylase 3 (HDAC3) Antibody (3G6): m-IgG Fc BP-HRP Bundle | sc-552890 | 200 µg Ab; 10 µg BP | $361.00 |