HDAC3 Antibody (1) is a mouse monoclonal IgG1 antibody that detects HDAC3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). HDAC3, or histone deacetylase 3, plays a crucial role in the regulation of gene expression by removing acetyl groups from histones, leading to chromatin condensation and transcriptional repression. This function is vital for maintaining cellular homeostasis and regulating various biological processes, including cell differentiation, proliferation, and apoptosis. Dysregulation of HDAC3 has been implicated in several diseases, including cancer and neurodegenerative disorders, making HDAC3 an important target for therapeutic intervention. HDAC3 is predominantly located in the nucleus, where HDAC3 interacts with various transcription factors and co-repressors to modulate gene expression. Understanding the dynamics of HDAC3 and its interactions can provide insights into the mechanisms of transcriptional regulation and the potential for developing targeted therapies. Anti-HDAC3 antibody (1) is an essential tool for researchers investigating the role of histone deacetylation in gene regulation and its implications in disease.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Histone Deacetylase 3 Antibody (1) | sc-130319 | 200 µg/ml | $316.00 | |||
Histone Deacetylase 3 (HDAC3) Antibody (1): m-IgG Fc BP-HRP Bundle | sc-539812 | 200 µg Ab; 10 µg BP | $354.00 | |||
Histone Deacetylase 3 (HDAC3) Antibody (1): m-IgG1 BP-HRP Bundle | sc-541724 | 200 µg Ab; 20 µg BP | $354.00 |