Date published: 2025-10-18

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Histone Deacetylase 3 (HDAC3) Antibody (1): sc-130319

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Datasheets
  • Histone Deacetylase 3 (HDAC3) Antibody (1) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
  • raised against recombinant HDAC3 of human origin
  • recommended for detection of HDAC3 of mouse, rat and human origin by WB, IP and ELISA
  • See Histone Deacetylase 3 (HDAC3) (A-3): sc-376957 for Histone Deacetylase 3 (HDAC3) antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Histone Deacetylase 3 (HDAC3) Antibody (1) for WB applications. These reagents are now offered in bundles with Histone Deacetylase 3 (HDAC3) Antibody (1) (see ordering information below).

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HDAC3 Antibody (1) is a mouse monoclonal IgG1 antibody that detects HDAC3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). HDAC3, or histone deacetylase 3, plays a crucial role in the regulation of gene expression by removing acetyl groups from histones, leading to chromatin condensation and transcriptional repression. This function is vital for maintaining cellular homeostasis and regulating various biological processes, including cell differentiation, proliferation, and apoptosis. Dysregulation of HDAC3 has been implicated in several diseases, including cancer and neurodegenerative disorders, making HDAC3 an important target for therapeutic intervention. HDAC3 is predominantly located in the nucleus, where HDAC3 interacts with various transcription factors and co-repressors to modulate gene expression. Understanding the dynamics of HDAC3 and its interactions can provide insights into the mechanisms of transcriptional regulation and the potential for developing targeted therapies. Anti-HDAC3 antibody (1) is an essential tool for researchers investigating the role of histone deacetylation in gene regulation and its implications in disease.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Histone Deacetylase 3 Antibody (1)

sc-130319
200 µg/ml
$316.00

Histone Deacetylase 3 (HDAC3) Antibody (1): m-IgG Fc BP-HRP Bundle

sc-539812
200 µg Ab; 10 µg BP
$354.00

Histone Deacetylase 3 (HDAC3) Antibody (1): m-IgG1 BP-HRP Bundle

sc-541724
200 µg Ab; 20 µg BP
$354.00

How much sample do you recommend loading on the gel for Western blot detection using HDAC3 (1): sc-130319?

Asked by: cjMara
We recommend loading 40–60 µg whole cell lysate, 10–20 µg nuclear extract, 5-10 µg transfected lysate, or 10–20 ng purified protein per lane. A link to our complete Western blotting protocol is provided here for your reference: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-01
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Rated 5 out of 5 by from Works well in human lung bronchial tissues in WBWorks well in human lung bronchial tissues in WB. -SCBT Publication Review
Date published: 2015-01-13
Rated 4 out of 5 by from Good monoclonal antibody and showed strongGood monoclonal antibody and showed strong band in recombinant HDAC in WB. -SCBT QC
Date published: 2013-02-22
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Histone Deacetylase 3 (HDAC3) Antibody (1) is rated 4.5 out of 5 by 2.
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