Histone Deacetylase 2 (HDAC2) Antibody (HDAC2-62): sc-56685
- Histone Deacetylase 2 (HDAC2) Antibody (HDAC2-62) is a mouse monoclonal IgG2b, cited in 4 publications, provided at 100 µg/ml
- raised against amino acids 471-488 of HDAC2 of human origin
- recommended for detection of HDAC2 of mouse, rat, human, bovine and canine origin by WB, IP and IF
- See Histone Deacetylase 2 (C-8): sc-9959 for Histone Deacetylase 2 (HDAC2) antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Histone Deacetylase 2 (HDAC2) Antibody (HDAC2-62). This work is in progress.
HDAC2 Antibody (HDAC2-62) is a mouse monoclonal IgG2b antibody that detects HDAC2 in mouse, rat, human, bovine, and canine samples through western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF) applications. HDAC2, or histone deacetylase 2, plays a crucial role in the regulation of gene expression by removing acetyl groups from histones, leading to a more compact chromatin structure that is less accessible to transcription factors. This deacetylation process is vital for maintaining cellular homeostasis and regulating various biological processes, including cell cycle progression, differentiation, and apoptosis. Dysregulation of HDAC2 has been implicated in several diseases, including cancer, where HDAC2 can contribute to the silencing of tumor suppressor genes. Furthermore, HDAC2 interacts with various proteins, such as the transcriptional co-repressor Sin3A and the NuRD complex, which are essential for HDAC2 function in transcriptional repression. HDAC2′s ability to modulate chromatin structure and gene expression underscores HDAC2′s importance in both normal cellular function and disease pathology, making anti-HDAC2 antibody (HDAC2-62) a valuable tool for researchers studying epigenetic regulation and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Histone Deacetylase 2 (HDAC2) Antibody (HDAC2-62) | sc-56685 | 100 µg/ml | $316.00 |