HAS2 Antibody (A-7): sc-514737

HAS2 Antibody (A-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects HAS2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HAS2 Antibody (A-7) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. HAS2, a member of the hyaluronan synthase family, plays a crucial role in synthesizing hyaluronic acid (HA), a vital component of the extracellular matrix that contributes to tissue hydration, elasticity, and cellular signaling. HA is a high molecular weight linear polysaccharide composed of alternating glucuronic acid and N-acetylglucosamine residues, linked by β-1,3 and β-1,4 glycosidic bonds. HAS2 synthesis of HA is particularly important in chondrocytes and cartilage, where HA supports the structural integrity and function of these tissues. HAS2 expression is notably upregulated in growing cells, indicating an essential role in development and tissue repair. The human HAS2 gene is located on chromosome 8q24.12, and distinct expression patterns during development highlight functional significance in various physiological processes.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-HAS2 Antibody (A-7) has 10 citations in a variety of scientific publications.

Primary antibodies like Anti-HAS2 Antibody (A-7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

HAS2 Antibody (A-7) Specifications

Alternate Product Name: hyaluronan synthase 2 (HAS2)

Product Clone Name: A-7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 121-180

Epitope Target: HAS2

Epitope Species: human

Product Reactivity/Detection: HAS2

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 10 citations in various scientific publications

Available Conjugates/Forms for HAS2 Antibody (A-7): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred HAS2 antibody is HAS2 Antibody (C-5): sc-365263.