GSTK1 Antibody (E-4): sc-515580
- GSTK1 Antibody (E-4) is a mouse monoclonal IgG2b κ GSTK1 antibody, cited in 4 publications, provided at 200 µg/ml
- raised against amino acids 1-226 representing full length GSTK1 of human origin
- GSTK1 Antibody (E-4) is recommended for detection of GSTK1 of human origin by WB, IP, IF and ELISA
- Anti-GSTK1 Antibody (E-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for GSTK1 Antibody (E-4) for WB applications. These reagents are now offered in bundles with GSTK1 Antibody (E-4) (see ordering information below).
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GSTK1 Antibody (E-4) is a mouse monoclonal IgG2b kappa light chain antibody that detects GSTK1 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GSTK1 (E-4) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. GSTK1, or glutathione S-transferase kappa 1, is a 226 amino acid protein that plays a crucial role in cellular detoxification, primarily localized in the peroxisome. GSTK1 exists as a homodimer and catalyzes the conjugation of glutathione to hydrophobic substrates, facilitating their removal from cells and protecting against toxicant-induced damage. GSTK1′s importance lies in detoxifying a wide range of xenobiotics, which is vital for maintaining cellular health and preventing oxidative stress. As a member of the glutathione S-transferase family, which includes eight distinct classes, GSTK1 contributes to a complex network of proteins that work together to safeguard cells from harmful compounds, underscoring its significance in both normal physiology and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
GSTK1 Antibody (E-4) References:
- Biochemical and genetic characterization of a murine class Kappa glutathione S-transferase. | Jowsey, IR., et al. 2003. Biochem J. 373: 559-69. PMID: 12720545
- Modelling and bioinformatics studies of the human Kappa-class glutathione transferase predict a novel third glutathione transferase family with similarity to prokaryotic 2-hydroxychromene-2-carboxylate isomerases. | Robinson, A., et al. 2004. Biochem J. 379: 541-52. PMID: 14709161
- Gene and protein characterization of the human glutathione S-transferase kappa and evidence for a peroxisomal localization. | Morel, F., et al. 2004. J Biol Chem. 279: 16246-53. PMID: 14742434
- Analysis of the glutathione S-transferase (GST) gene family. | Nebert, DW. and Vasiliou, V. 2004. Hum Genomics. 1: 460-4. PMID: 15607001
- [Advance in glutathione S-transferase kappa 1]. | Hu, C. and Sun, L. 2017. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 42: 468-475. PMID: 28490708
- Plasma mtDNA copy numbers are associated with GSTK1 expression and inflammation in type 2 diabetes. | Deng, X., et al. 2020. Diabet Med. 37: 1874-1878. PMID: 31502701
- Prognostic biomarker GSTK1 in head and neck squamous cell carcinoma and its correlation with immune infiltration and DNA methylation. | Feng, Y., et al. 2023. Front Genet. 14: 1041042. PMID: 36936420
- Functional Analysis of GSTK1 in Peroxisomal Redox Homeostasis in HEK-293 Cells. | Costa, CF., et al. 2023. Antioxidants (Basel). 12: PMID: 37371965
- m6A methylation-mediated PGC-1α contributes to ferroptosis via regulating GSTK1 in arsenic-induced hepatic insulin resistance. | Zhang, J., et al. 2023. Sci Total Environ. 905: 167202. PMID: 37730054
- Glutathione S-transferase class Kappa: characterization by the cloning of rat mitochondrial GST and identification of a human homologue. | Pemble, SE., et al. 1996. Biochem J. 319 (Pt 3): 749-54. PMID: 8920976
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GSTK1 Antibody (E-4) | sc-515580 | 200 µg/ml | $322.00 | |||
GSTK1 Antibody (E-4): m-IgG Fc BP-HRP Bundle | sc-531426 | 200 µg Ab; 10 µg BP | $361.00 | |||
GSTK1 Antibody (E-4): m-IgGκ BP-HRP Bundle | sc-525114 | 200 µg Ab, 40 µg BP | $361.00 | |||
GSTK1 Antibody (E-4): m-IgG2b BP-HRP Bundle | sc-550285 | 200 µg Ab; 10 µg BP | $361.00 | |||
GSTK1 Antibody (E-4) AC | sc-515580 AC | 500 µg/ml, 25% agarose | $424.00 | |||
GSTK1 Antibody (E-4) HRP | sc-515580 HRP | 200 µg/ml | $322.00 | |||
GSTK1 Antibody (E-4) FITC | sc-515580 FITC | 200 µg/ml | $336.00 | |||
GSTK1 Antibody (E-4) PE | sc-515580 PE | 200 µg/ml | $349.00 | |||
GSTK1 Antibody (E-4) Alexa Fluor® 488 | sc-515580 AF488 | 200 µg/ml | $364.00 | |||
GSTK1 Antibody (E-4) Alexa Fluor® 546 | sc-515580 AF546 | 200 µg/ml | $364.00 | |||
GSTK1 Antibody (E-4) Alexa Fluor® 594 | sc-515580 AF594 | 200 µg/ml | $364.00 | |||
GSTK1 Antibody (E-4) Alexa Fluor® 647 | sc-515580 AF647 | 200 µg/ml | $364.00 | |||
GSTK1 Antibody (E-4) Alexa Fluor® 680 | sc-515580 AF680 | 200 µg/ml | $364.00 | |||
GSTK1 Antibody (E-4) Alexa Fluor® 790 | sc-515580 AF790 | 200 µg/ml | $364.00 |