GRASP65 Antibody (G-9): sc-365412

GRASP65 Antibody (G-9) is a mouse monoclonal IgG2b antibody that detects GRASP65 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). GRASP65, also known as Golgi reassembly stacking protein 65, plays a crucial role in the organization and maintenance of the Golgi apparatus, a vital organelle involved in protein sorting and modification. GRASP65 is primarily located in the cis-Golgi and is essential for the stacking of Golgi cisternae, which is critical for the proper functioning of the secretory pathway. GRASP65 interacts with GRASP55 and is involved in the formation of a complex that facilitates the transport of proteins through the Golgi. GRASP65 undergoes post-translational modifications, including phosphorylation, which can influence function and stability. Phosphorylation of GRASP65 by mitogen-activated protein kinases during mitosis highlights GRASP65′s importance in cell cycle regulation and Golgi dynamics. Anti-GRASP65 antibody (G-9) enables researchers to gain insights into the mechanisms of Golgi organization and implications in cellular processes, making this tool invaluable for studies in cell biology and pathology.

The preferred GRASP65 antibody is GRASP65 Antibody (D-12): sc-374423.