granzyme M Antibody (C-10): sc-393375

granzyme M Antibody (C-10) is a mouse monoclonal IgG1 antibody that detects granzyme M in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Granzyme M, also known as NK cell granular protease or HU-Met-1, is a serine protease that plays a crucial role in the immune response by localizing to the granules of large granular lymphocytes, particularly natural killer (NK) cells and cytotoxic T lymphocytes. This protein is characterized by its Trypsin-fold serine protease structure, which allows cleavage of peptide substrates after specific amino acids such as leucine, norleucine, or methionine. Granzyme M′s ability to induce target cell death is vital for effective cell-mediated immune responses, as granzyme M helps eliminate infected or malignant cells. By understanding granzyme M′s function and importance, researchers can gain insights into its role in immune regulation and potential therapeutic applications in diseases where immune evasion is a factor. anti-granzyme M antibody (C-10) is an essential tool for studying this important protein and its implications in immunology.

The preferred granzyme M antibody is granzyme M Antibody (A-10): sc-376799.