GR/NR3C1/Glucocorticoid Receptor Antibody (F-10): sc-376426
- GR/NR3C1/Glucocorticoid Receptor Antibody (F-10) is a mouse monoclonal IgG2a κ, cited in 9 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 5-33 at the N-terminus of GR α of mouse origin
- recommended for detection of GR α and GR β of mouse and rat origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-376426 X, 200 µg/0.1 ml)
- See GR/NR3C1/Glucocorticoid Receptor (G-5): sc-393232 for GR/NR3C1/Glucocorticoid Receptor antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for GR/NR3C1/Glucocorticoid Receptor Antibody (F-10) for WB applications. These reagents are now offered in bundles with GR/NR3C1/Glucocorticoid Receptor Antibody (F-10) (see ordering information below).
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SEE ALSO...
GR Antibody (F-10) is a mouse monoclonal IgG2a antibody that detects glucocorticoid receptor (GR) in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-GR antibody (F-10) recognizes the most abundant isoform, GR α, which plays a crucial role as a transcription factor mediating the effects of glucocorticoids, influencing vital biological processes including apoptosis, cell growth, and differentiation. GR (F-10) antibody targets a protein that induces or represses gene expression in response to glucocorticoids, essential for maintaining homeostasis and regulating stress responses in the body. Notably, GR interacts with heat shock protein 90 (HSP 90), forming a complex that keeps the non-ligand bound receptor transcriptionally inactive, thereby highlighting the importance of this interaction in the regulation of GR activity. Furthermore, the presence of mutant GRs that lack the signaling domain and remain constitutively active underscores the significance of proper GR function in cellular signaling pathways. With robust reactivity and versatility in various applications, GR monoclonal antibody (F-10) serves as an invaluable tool for researchers studying glucocorticoid signaling and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GR/NR3C1/Glucocorticoid Receptor Antibody (F-10) | sc-376426 | 200 µg/ml | $322.00 | |||
GR/NR3C1/Glucocorticoid Receptor Antibody (F-10): m-IgG Fc BP-HRP Bundle | sc-540567 | 200 µg Ab; 10 µg BP | $361.00 | |||
GR/NR3C1/Glucocorticoid Receptor Antibody (F-10): m-IgG2a BP-HRP Bundle | sc-546926 | 200 µg Ab; 10 µg BP | $361.00 | |||
GR/NR3C1/Glucocorticoid Receptor (F-10) Neutralizing Peptide | sc-376426 P | 100 µg/0.5 ml | $69.00 | |||
GR/NR3C1/Glucocorticoid Receptor Antibody (F-10) X | sc-376426 X | 200 µg/0.1 ml | $322.00 |