GPT Antibody (G-9): sc-271089

GPT Antibody (G-9) is a mouse monoclonal IgG1 antibody that detects glutamate pyruvate transaminase (GPT) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-GPT antibody (G-9) recognizes GPT, which plays a crucial role in amino acid metabolism by catalyzing the reversible transamination between alanine and 2-oxoglutarate to produce pyruvate and glutamate. This enzymatic activity is vital for maintaining the balance of amino acids and energy production in the body, particularly in the liver, where GPT is predominantly expressed. GPT (G-9) antibody can detect protein localization in the cytoplasm of hepatocytes, where efficient processing of amino acids and glucose links carbohydrate and nitrogen metabolism. Elevated levels of GPT in the bloodstream are often indicative of liver damage, making GPT an important biomarker for assessing liver health. GPT monoclonal antibody (G-9) serves as an essential tool for researchers studying metabolic disorders, liver function, and biochemical pathways involving amino acids.

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GPT Antibody (G-9) References:

1. Linkage studies between HL-A and GPT polymorphisms and other genetic markers.  |  Goedde, HW., et al. 1976. Vox Sang. 30: 68-73. PMID: 1251571
2. Serum transaminase (GOT, GPT) and lactic dehydrogenase activity during treatment with methyl testosterone.  |  PETERA, V., et al. 1962. Clin Chim Acta. 7: 604-6. PMID: 13942711
3. Serum glutamic-oxaloacetic transaminase (GOT) and glutamic-pyruvic transaminase (GPT) levels in children and adolescents with intellectual disabilities.  |  Lin, JD., et al. 2010. Res Dev Disabil. 31: 172-7. PMID: 19828286
4. Usefulness of GPT for diagnosis of metabolic syndrome in obese Japanese children.  |  Abe, Y., et al. 2009. J Atheroscler Thromb. 16: 902-9. PMID: 20032584
5. Mismatched multiplex PCR amplification and subsequent RFLP analysis to simultaneously identify polymorphisms of erythrocytic ESD, GLO1, and GPT genes.  |  Pang, H., et al. 2011. J Forensic Sci. 56 Suppl 1: S176-8. PMID: 21198613
6. A comparative study of glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT) levels in the saliva of diabetic and normal patients.  |  Verma, M., et al. 2014. Biotech Histochem. 89: 529-34. PMID: 24849491
7. Serum glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) levels in diabetes mellitus.  |  Rao, GM., et al. 1989. Indian J Med Sci. 43: 118-21. PMID: 2793214
8. Identification of human red cell glutamate-pyruvate transaminase (GPT) phenotypes by isoelectric focusing.  |  Pelzer, CF. and Norum, RA. 1985. Am J Hum Genet. 37: 147-52. PMID: 3976656
9. Human red cell GPT polymorphism: comparison of the activities among different phenotypes using pyruvate and L-glutamate as substrates.  |  Ueda, S., et al. 1979. Jinrui Idengaku Zasshi. 24: 63-7. PMID: 529550
10. Human glutamate pyruvate transaminase (GPT): localization to 8q24.3, cDNA and genomic sequences, and polymorphic sites.  |  Sohocki, MM., et al. 1997. Genomics. 40: 247-52. PMID: 9119391

The preferred GPT antibody is GPT Antibody (E-3): sc-374501.