Date published: 2025-10-15

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GPT Inhibitors

GPT inhibitors belong to a specific chemical class of compounds that have been studied and designed to selectively target and inhibit the activity of GPT, which stands for Glutamic-pyruvic transaminase, also known as alanine aminotransferase (ALT). GPT is an enzyme that plays a crucial role in amino acid metabolism, specifically facilitating the transfer of amino groups between alanine and α-ketoglutarate.Inhibition of GPT aims to disrupt its catalytic function and modulate amino acid metabolism, affecting the balance of various amino acids in cells. The chemical structures of GPT inhibitors can vary, including synthetic small-molecule compounds and natural products that specifically interact with GPT and hinder its enzymatic activity or substrate binding. Researchers have explored various strategies to target GPT and regulate its role in amino acid metabolism, which is essential for various cellular processes. The study of GPT inhibitors provides valuable insights into the complex regulatory mechanisms governing amino acid homeostasis and cellular metabolism.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

rac Cycloserine

68-39-3sc-212728
100 mg
$262.00
1
(0)

Rac Cycloserine is a bicyclic compound that exhibits intriguing interactions with amino acid biosynthesis pathways. Its structural conformation allows it to mimic natural substrates, leading to competitive inhibition of enzymes involved in peptidoglycan synthesis. This mimicry alters reaction kinetics, resulting in a unique modulation of metabolic processes. Additionally, its polar functional groups enhance solubility, influencing its diffusion across biological membranes and interaction with target sites.

Isoniazid

54-85-3sc-205722
sc-205722A
sc-205722B
5 g
50 g
100 g
$25.00
$99.00
$143.00
(1)

Isoniazid has been studied for its potential to inhibit GPT activity.

Alrestatin

51411-04-2sc-201443
sc-201443A
10 mg
50 mg
$113.00
$510.00
(0)

Some aldose reductase inhibitors have shown inhibitory effects on GPT activity, although their primary target is aldose reductase.