Glucose Transporter Glut10 Antibody (H-10): sc-398495
- Glucose Transporter Glut10 Antibody (H-10) is a mouse monoclonal IgG1 κ Glucose Transporter Glut10 antibody provided at 200 µg/ml
- raised against amino acids 321-416 mapping within an extracellular domain of Glut10 of human origin
- Glucose Transporter Glut10 Antibody (H-10) is recommended for detection of Glut10 of mouse, rat, human origin by WB, IP, IF and ELISA
- Anti-Glucose Transporter Glut10 Antibody (H-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Glucose Transporter Glut10 Antibody (H-10) for WB applications. These reagents are now offered in bundles with Glucose Transporter Glut10 Antibody (H-10) (see ordering information below).
Glut10 Antibody (H-10) is a mouse monoclonal IgG1 kappa light chain antibody that detects Glut10 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-Glut10 antibody (H-10) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Glut10 protein, also known as SLC2A10, plays a crucial role in glucose transport, which is essential for cellular metabolism and energy production. This 541 amino acid facilitative glucose transporter is predominantly expressed in the liver and pancreas, where Glut10 facilitates the uptake of glucose, a vital energy source for mammalian cells. SLC2A10 is characterized by 12 transmembrane domains, which create a pathway for glucose to traverse the cell membrane, and features a hydrophilic intracellular loop between helices 6 and 7, as well as a large extracellular loop between helices 9 and 10 that may contain a potential N-linked glycosylation site. The gene encoding Glut10, SLC2A10, is located on chromosome 20q13.1, a region associated with type 2 diabetes, highlighting SLC2A10′s importance in metabolic regulation and potential implications in diabetes research.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Glucose Transporter Glut10 Antibody (H-10) References:
- Molecular cloning of a novel member of the GLUT family of transporters, SLC2a10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility. | McVie-Wylie, AJ., et al. 2001. Genomics. 72: 113-7. PMID: 11247674
- Sequence and functional analysis of GLUT10: a glucose transporter in the Type 2 diabetes-linked region of chromosome 20q12-13.1. | Dawson, PA., et al. 2001. Mol Genet Metab. 74: 186-99. PMID: 11592815
- Cytokine regulation of facilitated glucose transport in human articular chondrocytes. | Shikhman, AR., et al. 2001. J Immunol. 167: 7001-8. PMID: 11739520
- The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review). | Joost, HG. and Thorens, B. 2001. Mol Membr Biol. 18: 247-56. PMID: 11780753
- Genetic variation of the GLUT10 glucose transporter (SLC2A10) and relationships to type 2 diabetes and intermediary traits. | Andersen, G., et al. 2003. Diabetes. 52: 2445-8. PMID: 12941788
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Glucose Transporter Glut10 Antibody (H-10) | sc-398495 | 200 µg/ml | $316.00 | |||
Glucose Transporter Glut10 Antibody (H-10): m-IgG Fc BP-HRP Bundle | sc-530819 | 200 µg Ab; 10 µg BP | $354.00 | |||
Glucose Transporter Glut10 Antibody (H-10): m-IgGκ BP-HRP Bundle | sc-524365 | 200 µg Ab, 40 µg BP | $354.00 | |||
Glucose Transporter Glut10 Antibody (H-10): m-IgG1 BP-HRP Bundle | sc-544265 | 200 µg Ab; 20 µg BP | $354.00 | |||
Glucose Transporter Glut10 Antibody (H-10) AC | sc-398495 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Glucose Transporter Glut10 Antibody (H-10) HRP | sc-398495 HRP | 200 µg/ml | $316.00 | |||
Glucose Transporter Glut10 Antibody (H-10) FITC | sc-398495 FITC | 200 µg/ml | $330.00 | |||
Glucose Transporter Glut10 Antibody (H-10) PE | sc-398495 PE | 200 µg/ml | $343.00 | |||
Glucose Transporter Glut10 Antibody (H-10) Alexa Fluor® 488 | sc-398495 AF488 | 200 µg/ml | $357.00 | |||
Glucose Transporter Glut10 Antibody (H-10) Alexa Fluor® 546 | sc-398495 AF546 | 200 µg/ml | $357.00 | |||
Glucose Transporter Glut10 Antibody (H-10) Alexa Fluor® 594 | sc-398495 AF594 | 200 µg/ml | $357.00 | |||
Glucose Transporter Glut10 Antibody (H-10) Alexa Fluor® 647 | sc-398495 AF647 | 200 µg/ml | $357.00 | |||
Glucose Transporter Glut10 Antibody (H-10) Alexa Fluor® 680 | sc-398495 AF680 | 200 µg/ml | $357.00 | |||
Glucose Transporter Glut10 Antibody (H-10) Alexa Fluor® 790 | sc-398495 AF790 | 200 µg/ml | $357.00 |