GLTP Antibody (C-3): sc-514289
- GLTP Antibody (C-3) is a mouse monoclonal IgG2a κ GLTP antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 36-57 within an internal region of GLTP of human origin
- GLTP Antibody (C-3) is recommended for detection of GLTP of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-GLTP Antibody (C-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for GLTP Antibody (C-3) for WB applications. These reagents are now offered in bundles with GLTP Antibody (C-3) (see ordering information below).
QUICK LINKS
SEE ALSO...
GLTP Antibody (C-3) is a mouse monoclonal IgG2a kappa light chain antibody that detects GLTP protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GLTP (C-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. GLTP, or glycolipid transfer protein, consists of 209 amino acids and plays a key role in lipid metabolism by facilitating glycosphingolipid transfer between cellular membranes. This function maintains membrane integrity and fluidity, while ensuring proper distribution of glycolipids essential for cell signaling and recognition processes. GLTP shows high conservation across mammalian species and primarily localizes in the cytoplasm as a monomer. GLTP genes reside on human chromosome 12q24.11 and mouse chromosome 5 F, with expression observed in various cell types, including fibroblasts and several cancer cell lines, suggesting roles in both normal physiology and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
GLTP Antibody (C-3) References:
- Charged membrane surfaces impede the protein-mediated transfer of glycosphingolipids between phospholipid bilayers. | Mattjus, P., et al. 2000. Biochemistry. 39: 1067-75. PMID: 10653652
- Human glycolipid transfer protein: probing conformation using fluorescence spectroscopy. | Li, XM., et al. 2004. Biochemistry. 43: 10285-94. PMID: 15287756
- Structural basis for glycosphingolipid transfer specificity. | Malinina, L., et al. 2004. Nature. 430: 1048-53. PMID: 15329726
- Glycolipid transfer protein mediated transfer of glycosphingolipids between membranes: a model for action based on kinetic and thermodynamic analyses. | Rao, CS., et al. 2004. Biochemistry. 43: 13805-15. PMID: 15504043
- Point mutational analysis of the liganding site in human glycolipid transfer protein. Functionality of the complex. | Malakhova, ML., et al. 2005. J Biol Chem. 280: 26312-20. PMID: 15901739
- Structural evidence for adaptive ligand binding of glycolipid transfer protein. | Airenne, TT., et al. 2006. J Mol Biol. 355: 224-36. PMID: 16309699
- Human glycolipid transfer protein--intracellular localization and effects on the sphingolipid synthesis. | Tuuf, J. and Mattjus, P. 2007. Biochim Biophys Acta. 1771: 1353-63. PMID: 17980653
- Human GLTP: Three distinct functions for the three tryptophans in a novel peripheral amphitropic fold. | Kamlekar, RK., et al. 2010. Biophys J. 99: 2626-35. PMID: 20959104
- Human glycolipid transfer protein gene (GLTP) expression is regulated by Sp1 and Sp3: involvement of the bioactive sphingolipid ceramide. | Zou, X., et al. 2011. J Biol Chem. 286: 1301-11. PMID: 20974858
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GLTP Antibody (C-3) | sc-514289 | 200 µg/ml | $316.00 | |||
GLTP Antibody (C-3): m-IgG Fc BP-HRP Bundle | sc-531080 | 200 µg Ab; 10 µg BP | $354.00 | |||
GLTP Antibody (C-3): m-IgGκ BP-HRP Bundle | sc-524674 | 200 µg Ab, 40 µg BP | $354.00 | |||
GLTP Antibody (C-3): m-IgG2a BP-HRP Bundle | sc-547680 | 200 µg Ab; 10 µg BP | $354.00 | |||
GLTP Antibody (C-3) AC | sc-514289 AC | 500 µg/ml, 25% agarose | $416.00 | |||
GLTP Antibody (C-3) HRP | sc-514289 HRP | 200 µg/ml | $316.00 | |||
GLTP Antibody (C-3) FITC | sc-514289 FITC | 200 µg/ml | $330.00 | |||
GLTP Antibody (C-3) PE | sc-514289 PE | 200 µg/ml | $343.00 | |||
GLTP Antibody (C-3) Alexa Fluor® 488 | sc-514289 AF488 | 200 µg/ml | $357.00 | |||
GLTP Antibody (C-3) Alexa Fluor® 546 | sc-514289 AF546 | 200 µg/ml | $357.00 | |||
GLTP Antibody (C-3) Alexa Fluor® 594 | sc-514289 AF594 | 200 µg/ml | $357.00 | |||
GLTP Antibody (C-3) Alexa Fluor® 647 | sc-514289 AF647 | 200 µg/ml | $357.00 | |||
GLTP Antibody (C-3) Alexa Fluor® 680 | sc-514289 AF680 | 200 µg/ml | $357.00 | |||
GLTP Antibody (C-3) Alexa Fluor® 790 | sc-514289 AF790 | 200 µg/ml | $357.00 | |||
GLTP (C-3) Neutralizing Peptide | sc-514289 P | 100 µg/0.5 ml | $68.00 |