GKLF/KLF4 Antibody (A-2): sc-166190
- GKLF/KLF4 Antibody (A-2) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 1-180 of GKLF of human origin
- recommended for detection of GKLF of human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-166190 X, 200 µg/0.1 ml)
- See GKLF/EKLF/LKLF/KLF4/1/2 (F-8): sc-166238 for GKLF/KLF4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for GKLF/KLF4 Antibody (A-2) for WB applications. These reagents are now offered in bundles with GKLF/KLF4 Antibody (A-2) (see ordering information below).
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SEE ALSO...
GKLF Antibody (A-2) is a mouse monoclonal IgG1 kappa antibody raised against amino acids 1-180 of human GKLF, also known as Kruppel-like factor 4 (KLF4). Anti-GKLF antibody (A-2) is validated for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA), with species reactivity limited to human proteins. KLF4 is a member of the Kruppel-like factor family, a group of transcription factors characterized by zinc finger domains, which are critical for binding DNA. The zinc finger structure consists of repeated motifs that interact specifically with DNA sequences, allowing KLF4 to regulate gene expression involved in cellular processes such as proliferation, differentiation, and stress response. This structural feature maintains epithelial integrity and regulates cell cycle arrest, particularly in tissues like the gastrointestinal tract and skin. KLF4′s ability to modulate gene expression through zinc finger domains makes KLF4 a key player in development and cellular homeostasis. Dysregulation of KLF4 has been linked to various pathological conditions, including cancer, underscoring the importance of structural integrity for proper function. Anti-KLF4 antibody (A-2) serves as a valuable tool for studying structural and functional roles in development and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GKLF/KLF4 Antibody (A-2) | sc-166190 | 200 µg/ml | $322.00 | |||
GKLF/KLF4 Antibody (A-2): m-IgG Fc BP-HRP Bundle | sc-540038 | 200 µg Ab; 10 µg BP | $361.00 | |||
GKLF/KLF4 Antibody (A-2): m-IgG1 BP-HRP Bundle | sc-541863 | 200 µg Ab; 20 µg BP | $361.00 | |||
GKLF/KLF4 Antibody (A-2) X | sc-166190 X | 200 µg/0.1 ml | $322.00 |