Anti-GIT1 Antibody (A-1) is a mouse monoclonal IgG1 κ GIT1 antibody, cited in 1 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 7-35 near the N-terminus of GIT1 of rat origin
Anti-GIT1 Antibody (A-1) is recommended for detection of GIT1 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-GIT1 Antibody (A-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of GIT1 (A-1): sc-365084.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred detection reagent for GIT1 Antibody (A-1) for WB applications. This reagent is now offered in a bundle with GIT1 Antibody (A-1) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
GIT1 Antibody (A-1) is a high quality monoclonal GIT1 antibody (also designated GIT ArfGAP 1 antibody, G Protein-Coupled Receptor Kinase Interacting ArfGAP antibody, Cool-Associated And Tyrosine-Phosphorylated Protein antibody, G Protein-Coupled Receptor Kinase-Interactor antibody, ARF GTPase-Activating Protein GIT1 antibody, GRK-Interacting Protein 1 antibody, ARF GAP GIT1 antibody, CAT-1 antibody, CAT1 antibody, or G Protein-Coupled Receptor Kinase Interactor antibody) suitable for the detection of the GIT1 protein of mouse, rat and human origin. GIT1 Antibody (A-1) is available as both the non-conjugated anti-GIT1 antibody form, as well as multiple conjugated forms of anti-GIT1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade. GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking. GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences