Gemin4 Antibody (A-2): sc-166016
- Gemin4 Antibody (A-2) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1019-1053 at the C-terminus of Gemin4 of human origin
- recommended for detection of Gemin4 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Gemin4 Antibody (A-2) for WB applications. These reagents are now offered in bundles with Gemin4 Antibody (A-2) (see ordering information below).
Gemin4 Antibody (A-2) is a mouse monoclonal IgG1 antibody that detects Gemin4 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Gemin4 is a crucial component of the SMN core complex, which is vital for the assembly of small nuclear ribonucleoproteins (snRNPs) in the cytoplasm, facilitating their biogenesis, delivery, and recycling to the spliceosome. In the nucleus, Gemin4 is predominantly located near coiled bodies within subnuclear structures known as gems, which are rich in splicing factors and snRNPs, playing a significant role in pre-mRNA splicing. The importance of Gemin4 extends to its involvement in spinal muscular atrophy (SMA), a neurodegenerative disease caused by the deletion or loss-of-function mutations in the SMN complex, highlighting Gemin4′s critical function in maintaining neuronal health. Additionally, the human Gemin4 gene is mapped to chromosome 17p13.3, underscoring its genetic significance. Anti-Gemin4 antibody (A-2) is an essential tool for researchers studying RNA processing and related pathologies, providing reliable detection and characterization of this important protein.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Gemin4 Antibody (A-2) | sc-166016 | 200 µg/ml | $322.00 | |||
Gemin4 Antibody (A-2): m-IgG Fc BP-HRP Bundle | sc-537430 | 200 µg Ab; 10 µg BP | $361.00 | |||
Gemin4 Antibody (A-2): m-IgGκ BP-HRP Bundle | sc-534692 | 200 µg Ab; 40 µg BP | $361.00 | |||
Gemin4 Antibody (A-2): m-IgG1 BP-HRP Bundle | sc-545181 | 200 µg Ab; 20 µg BP | $361.00 | |||
Gemin4 (A-2) Neutralizing Peptide | sc-166016 P | 100 µg/0.5 ml | $69.00 |