Anti-Gemin4 Antibody (E-8) is a mouse monoclonal IgG1 κ Gemin4 antibody, cited in 2 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 1019-1053 at the C-terminus of Gemin4 of human origin
Gemin4 Antibody (E-8) is recommended for detection of Gemin4 of human origin by WB, IP, IF, IHC(P) and ELISA
Anti-Gemin4 Antibody (E-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of Gemin4 (E-8): sc-365424.
m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Gemin4 Antibody (E-8) for WB and IHC(P) applications. These reagents are now offered in bundles with Gemin4 Antibody (E-8) (see ordering information below).
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possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Gemin4 Antibody (E-8) is a high quality monoclonal Gemin4 antibody (also designated Gemin4 antibody) suitable for the detection of the Gemin4 protein of human origin. Gemin4 Antibody (E-8) is available as both the non-conjugated anti-Gemin4 antibody form, as well as multiple conjugated forms of anti-Gemin4 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Gemin4 is a component of the SMN core complex which, while in the cytoplasm, plays an essential role in ribonucleoprotein (snRNP) assembly, including the biogenesis, delivery and recycling of snRNPs to the spliceosome. In the nucleus, where SMN is required for pre-mRNA splicing, Gemin4 concentrates next to coiled bodies in subnuclear structures called gems, that are highly enriched in splicosomal snRNPs, and in the nucleolus. Deletion or loss-of-function mutations in the SMN lead to the neurodegenerative disease spinal muscular atrophy (SMA). The human Gemin4 maps to chromosome 17p13.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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