GDF-8/11 Antibody (A-1): sc-398333
- GDF-8/11 Antibody (A-1) is a mouse monoclonal IgG2b κ GDF-8/11 antibody, cited in 4 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 258-270 within an internal region of GDF-8 of human origin
- recommended for detection of precursor and mature GDF-8 and GDF-11 of mouse, rat, human and origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- See GDF-8/11 (H-9): sc-393335 for GDF-8/11 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for GDF-8/11 Antibody (A-1) for WB applications. This reagent is now offered in a bundle with GDF-8/11 Antibody (A-1) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
GDF-8/11 Antibody (A-1) is a mouse monoclonal IgG2b kappa light chain antibody that detects GDF-8/11 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-GDF-8/11 antibody (A-1) is available as the non-conjugated form. GDF-8/11 protein, which includes myostatin, plays a crucial role in regulating muscle growth and development. Myostatin is primarily expressed in skeletal muscle and functions as a negative regulator of muscle differentiation and growth, making GDF-8/11 essential for maintaining muscle mass and preventing excessive muscle hypertrophy. Dysregulation of myostatin can lead to muscle-wasting diseases and conditions such as cachexia, highlighting GDF-8/11′s importance in both health and disease. GDF-11, another member of this protein family, is involved in various developmental processes, including organogenesis regulation in kidney and pancreas, as well as axial skeleton patterning. GDF-11′s ability to influence gene expression of GDNF and HOX further underscores GDF-11′s significance in developmental biology. With diverse roles in muscle regulation and organ development, GDF-8/11 monoclonal antibody (A-1) serves as a valuable tool for researchers studying these critical biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GDF-8/11 Antibody (A-1) | sc-398333 | 200 µg/ml | $316.00 | |||
GDF-8/11 Antibody (A-1): m-IgGκ BP-HRP Bundle | sc-536034 | 200 µg Ab; 40 µg BP | $354.00 | |||
GDF-8/11 (A-1) Neutralizing Peptide | sc-398333 P | 100 µg/0.5 ml | $68.00 |