GDF-8/11 Antibody (H-9): sc-393335
- GDF-8/11 Antibody (H-9) is a mouse monoclonal IgG2a κ, cited in 12 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 347-376 at the C-terminus of GDF-8 of mouse origin
- Anti-GDF-8/11 Antibody (H-9) is recommended for detection of precursor and mature GDF-8 and GDF-11 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-GDF-8/11 Antibody (H-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2a BP-HRP is the preferred secondary detection reagent for GDF-8/11 Antibody (H-9) for WB and IHC(P) applications. This reagent is now offered in a bundle with GDF-8/11 Antibody (H-9) (see ordering information below).
GDF-8/11 Antibody (H-9) is a mouse monoclonal IgG2a kappa light chain antibody that detects GDF-8/11 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). GDF-8/11 (H-9) antibody is available in both non-conjugated and multiple conjugated forms, such as agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates. The growth/differentiation factors (GDFs), which belong to the transforming growth factor-beta (TGF-β) superfamily, play crucial roles in embryonic development and the maintenance of adult tissue homeostasis. GDF-8, commonly referred to as myostatin, serves as a negative regulator of skeletal muscle growth, making GDF-8 vital for understanding muscle development and potential therapeutic targets for muscle-wasting diseases. GDF-11 is essential for anterior/posterior patterning of the axial skeleton and regulates organogenesis in the kidney and pancreas by influencing the expression of glial cell line-derived neurotrophic factor (GDNF). GDF-11 is involved in the control of HOX gene expression, induces phosphorylation of Smad2, mediates Nodal signaling during left-right patterning, and plays a role in the development of head structures while inhibiting the generation of new neurons from progenitor cells in the olfactory epithelium.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GDF-8/11 Antibody (H-9) | sc-393335 | 200 µg/ml | $316.00 | |||
GDF-8/11 Antibody (H-9): m-IgG2a BP-HRP Bundle | sc-545965 | 200 µg Ab; 10 µg BP | $354.00 | |||
GDF-8/11 Antibody (H-9) AC | sc-393335 AC | 500 µg/ml, 25% agarose | $416.00 | |||
GDF-8/11 Antibody (H-9) HRP | sc-393335 HRP | 200 µg/ml | $316.00 | |||
GDF-8/11 Antibody (H-9) FITC | sc-393335 FITC | 200 µg/ml | $330.00 | |||
GDF-8/11 Antibody (H-9) PE | sc-393335 PE | 200 µg/ml | $343.00 | |||
GDF-8/11 Antibody (H-9) Alexa Fluor® 488 | sc-393335 AF488 | 200 µg/ml | $357.00 | |||
GDF-8/11 Antibody (H-9) Alexa Fluor® 546 | sc-393335 AF546 | 200 µg/ml | $357.00 | |||
GDF-8/11 Antibody (H-9) Alexa Fluor® 594 | sc-393335 AF594 | 200 µg/ml | $357.00 | |||
GDF-8/11 Antibody (H-9) Alexa Fluor® 647 | sc-393335 AF647 | 200 µg/ml | $357.00 | |||
GDF-8/11 Antibody (H-9) Alexa Fluor® 680 | sc-393335 AF680 | 200 µg/ml | $357.00 | |||
GDF-8/11 Antibody (H-9) Alexa Fluor® 790 | sc-393335 AF790 | 200 µg/ml | $357.00 | |||
GDF-8/11 (H-9) Neutralizing Peptide | sc-393335 P | 100 µg/0.5 ml | $68.00 |