GCM2 Antibody (C-2): sc-514736
- GCM2 Antibody (C-2) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 25-45 near the N-terminus of GCM2 of mouse origin
- recommended for detection of GCM2 of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-514736 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for GCM2 Antibody (C-2) for WB applications. These reagents are now offered in bundles with GCM2 Antibody (C-2) (see ordering information below).
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GCM2 Antibody (C-2) is a mouse monoclonal IgG1 antibody that detects glial cells missing homolog 2 (GCM2) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GCM2 is a crucial nuclear protein composed of 506 amino acids that functions as a transcription factor, playing a vital role in the regulation of parathyroid development. Anti-GCM2 antibody (C-2) recognizes a protein particularly important for mediating the effects of calcium on the expression and secretion of parathyroid hormone in parathyroid cells, which is essential for maintaining calcium homeostasis in the body. GCM2 contains a unique N-terminal GCM domain that exhibits DNA binding activity, allowing interaction with specific gene promoters and regulation of their transcription. Notably, mutations in the gene encoding GCM2 have been linked to hypoparathyroidism, an autosomal recessive disorder characterized by low calcium levels and elevated phosphate levels, underscoring the significance of GCM2 in endocrine function and calcium regulation. GCM2 (C-2) antibody serves as an invaluable tool for researchers studying parathyroid biology and related disorders, providing reliable detection and analysis of this critical protein.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GCM2 Antibody (C-2) | sc-514736 | 200 µg/ml | $316.00 | |||
GCM2 Antibody (C-2): m-IgG Fc BP-HRP Bundle | sc-538693 | 200 µg Ab; 10 µg BP | $354.00 | |||
GCM2 Antibody (C-2): m-IgGκ BP-HRP Bundle | sc-536355 | 200 µg Ab; 40 µg BP | $354.00 | |||
GCM2 Antibody (C-2): m-IgG1 BP-HRP Bundle | sc-545836 | 200 µg Ab; 20 µg BP | $354.00 | |||
GCM2 (C-2) Neutralizing Peptide | sc-514736 P | 100 µg/0.5 ml | $68.00 | |||
GCM2 Antibody (C-2) X | sc-514736 X | 200 µg/0.1 ml | $316.00 |