GATA-6 Antibody (F-3): sc-518050

GATA-6 Antibody (F-3) is a mouse monoclonal IgM antibody that detects GATA-6 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GATA-6 Antibody (F-3) is available in a non-conjugated form, allowing for versatile applications in various experimental settings. GATA-6 is a member of the GATA family of transcription factors, characterized by a conserved zinc finger DNA-binding domain that binds to specific DNA sequences, particularly the WGATAR consensus sequence. GATA-6 plays a crucial role in gene expression regulation during development, particularly in heart, pancreas, and reproductive tissues. GATA-6 is essential for proper differentiation and function of various cell types, including cardiac myocytes and endocrine cells. GATA-6 expression is tightly regulated and interacts with other GATA family members, such as GATA-4 and GATA-5, to coordinate complex gene regulatory networks. Understanding GATA-6 interactions and regulatory mechanisms is vital, as dysregulation has been implicated in various developmental disorders and diseases, including congenital heart defects and certain cancers. GATA-6′s ability to form heterodimers with other GATA factors enhances regulatory capabilities, making GATA-6 a key player in transcriptional control of genes critical for cellular identity and function.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-GATA-6 Antibody (F-3) has 2 citations in a variety of scientific publications.

Primary antibodies like Anti-GATA-6 Antibody (F-3) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

GATA-6 Antibody (F-3) Specifications

Alternate Product Name: GATA6

Product Clone Name: F-3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 44-69

Epitope Target: GATA-6

Epitope Species: human

Product Reactivity/Detection: GATA-6

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 2 citations in various scientific publications

Available Conjugates/Forms for GATA-6 Antibody (F-3): N/A

The preferred GATA-6 antibody is GATA-6 Antibody (3H3-H6-H11): sc-517554.