Ganglioside GD3 Antibody (2Q631): sc-71139

Ganglioside GD3 Antibody (2Q631) is a mouse monoclonal IgG3 kappa light chain antibody that detects Ganglioside GD3 of human origin by immunofluorescence (IF) and flow cytometry (FCM). Anti-Ganglioside GD3 antibody (2Q631) is available in both non-conjugated and various conjugated forms, including phycoerythrin (PE) and fluorescein isothiocyanate (FITC), providing versatility for different experimental needs. Ganglioside GD3 is a crucial glycosphingolipid found in cell membranes, playing a significant role in cell signaling and interaction. The structure, characterized by a sialic acid residue attached to a ceramide backbone, is essential for mediating cell adhesion and growth, particularly in malignant cells. Ganglioside GD3 levels notably increase in pathological conditions, such as cancer, where Ganglioside GD3 contributes to the upregulation of signaling pathways that promote cell survival and proliferation. Ganglioside GD3 also regulates apoptosis, acting as a key player in mitochondrial damage and influencing cell fate decisions. Understanding Ganglioside GD3 expression dynamics and interactions with other proteins is vital for elucidating roles in both normal physiology and disease states, making Ganglioside GD3 (2Q631) monoclonal antibody an invaluable research tool.

The preferred Ganglioside GD3 antibody is Ganglioside GD3 Antibody (MB3.6): sc-33685.