γ Tubulin Antibody (TU-30): sc-51715

γ Tubulin Antibody (TU-30) is a mouse monoclonal IgG1 antibody that detects γ Tubulin from mouse, rat, human, and porcine origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). anti-γ Tubulin antibody (TU-30) is available in non-conjugated form. γ Tubulin plays a crucial role in forming the gammasome, a complex essential for nucleating microtubule filaments at the centrosome, which is vital for proper cell division and cytoskeleton organization. The gammasome serves as a template for microtubule assembly, ensuring microtubules are correctly oriented and anchored, which is critical for maintaining cell shape, intracellular transport, and chromosome segregation during mitosis. γ Tubulin (TU-30) antibody helps researchers study how γ Tubulin regulates microtubule dynamics, influencing cellular processes like migration and signaling. γ Tubulin′s presence at the centrosome and interaction with other tubulin isoforms underscores its importance in cytoskeleton architecture and function, making γ Tubulin (TU-30) monoclonal antibody an invaluable tool for studying cellular structure and dynamics.

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γ Tubulin Antibody (TU-30) References:

1. The BRCA1-dependent ubiquitin ligase, gamma-tubulin, and centrosomes.  |  Parvin, JD. 2009. Environ Mol Mutagen. 50: 649-53. PMID: 19274767
2. Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. II. gamma-Tubulin.  |  Katsetos, CD., et al. 2009. J Cell Physiol. 221: 514-20. PMID: 19650077
3. Assembly of gamma-tubulin ring complexes: implications for cell biology and disease.  |  Remy, MH., et al. 2013. Prog Mol Biol Transl Sci. 117: 511-30. PMID: 23663981
4. γ-Tubulin complexes in microtubule nucleation and beyond.  |  Oakley, BR., et al. 2015. Mol Biol Cell. 26: 2957-62. PMID: 26316498
5. Characterization of gamma-tubulin filaments in mammalian cells.  |  Lindström, L. and Alvarado-Kristensson, M. 2018. Biochim Biophys Acta Mol Cell Res. 1865: 158-171. PMID: 29050966
6. Non-Canonical Functions of the Gamma-Tubulin Meshwork in the Regulation of the Nuclear Architecture.  |  Corvaisier, M. and Alvarado-Kristensson, M. 2020. Cancers (Basel). 12: PMID: 33114224
7. Proteolysis of γ-tubulin small complex proteins is mediated by the ubiquitin-proteasome system.  |  Yin, C., et al. 2021. FEBS Lett. 595: 1987-1996. PMID: 34107052
8. The γ-tubulin meshwork assists in the recruitment of PCNA to chromatin in mammalian cells.  |  Corvaisier, M., et al. 2021. Commun Biol. 4: 767. PMID: 34158617
9. Structure of the native γ-tubulin ring complex capping spindle microtubules.  |  Dendooven, T., et al. 2024. Nat Struct Mol Biol. 31: 1134-1144. PMID: 38609662
10. γ-tubulin complex controls the nucleation of tubulin-based structures in Apicomplexa.  |  Haase, R., et al. 2024. Mol Biol Cell. 35: ar121. PMID: 39046777

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-γ Tubulin Antibody (TU-30) has 37 citations in a variety of scientific publications.

Primary antibodies like Anti-γ Tubulin Antibody (TU-30) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

γ Tubulin Antibody (TU-30) Specifications

Alternate Product Name: gamma Tubulin

Product Clone Name: TU-30

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: γ Tubulin

Epitope Species: human

Product Reactivity/Detection: γ Tubulin

Species Reactivity/Detection: mouse, rat, human, porcine

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 37 citations in various scientific publications

Available Conjugates/Forms for γ Tubulin Antibody (TU-30): N/A

The preferred γ Tubulin antibody is γ Tubulin Antibody (D-10): sc-17788.