γ Enolase Antibody (NSE-P2): sc-21737
- γ Enolase Antibody (NSE-P2) is a mouse monoclonal IgG1 κ, cited in 11 publications, provided at 200 µg/ml
- raised against amino acids 271-285 of γ Enolase of human origin
- Anti-gamma Enolase Antibody (NSE-P2) is recommended for detection of γ Enolase of mouse, rat and human origin by WB, IP and IF
- Anti-gamma Enolase Antibody (NSE-P2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for γ Enolase Antibody (NSE-P2) for WB applications. These reagents are now offered in bundles with γ Enolase Antibody (NSE-P2) (see ordering information below).
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γ Enolase Antibody (NSE-P2) is a mouse monoclonal IgG1 kappa light chain antibody that detects γ Enolase in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-γ Enolase antibody (NSE-P2) is offered in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. γ Enolase, one of three enolase isoforms, is primarily localized in nervous tissue, where γ Enolase plays a crucial role in the glycolytic pathway by catalyzing the conversion of 2-phosphoglycerate to phosphoenolpyruvate, a key step in energy production. This localization is significant as γ Enolase highlights the enzyme′s importance in neuronal metabolism and function, particularly in the context of energy demands in the brain. γ Enolase presence in the nervous system also suggests involvement in neurodevelopment and neurodegenerative processes, making γ Enolase a valuable target for research in neurological disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
γ Enolase Antibody (NSE-P2) References:
- Arsenic, cadmium and neuron specific enolase (ENO2, γ-enolase) expression in breast cancer. | Soh, MA., et al. 2011. Cancer Cell Int. 11: 41. PMID: 22098917
- Identification of Autoantibodies for α and γ-Enolase in Serum from a Patient with Melanoma. | Hiura, Y., et al. 2011. Jpn Clin Med. 2: 35-41. PMID: 23885189
- Gamma-enolase: a well-known tumour marker, with a less-known role in cancer. | Vizin, T. and Kos, J. 2015. Radiol Oncol. 49: 217-26. PMID: 26401126
- Gamma-enolase predicts lung damage in severe acute pancreatitis-induced acute lung injury. | Owusu, L., et al. 2018. J Mol Histol. 49: 347-356. PMID: 29728894
- Evaluation of gamma-enolase as a tumor marker for lung cancer. | Fujita, K., et al. 1987. Cancer. 60: 362-9. PMID: 3036329
- γ-Enolase enhances Trk endosomal trafficking and promotes neurite outgrowth in differentiated SH-SY5Y cells. | Pišlar, A. and Kos, J. 2021. Cell Commun Signal. 19: 118. PMID: 34895236
- Upregulation of Cathepsin X in Glioblastoma: Interplay with γ-Enolase and the Effects of Selective Cathepsin X Inhibitors. | Majc, B., et al. 2022. Int J Mol Sci. 23: PMID: 35163706
- γ-enolase (ENO2) is methylated at the Nτ position of His-190 among enolase isozymes. | Kasai, F., et al. 2023. J Biochem. 174: 279-289. PMID: 37279646
- Multifunctional roles of γ-enolase in the central nervous system: more than a neuronal marker. | Horvat, S., et al. 2024. Cell Biosci. 14: 61. PMID: 38735971
- Use of serum gamma-enolase and aldolase A in combination as markers for renal cell carcinoma. | Takashi, M., et al. 1993. Jpn J Cancer Res. 84: 304-9. PMID: 8486529
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
γ Enolase Antibody (NSE-P2) | sc-21737 | 200 µg/ml | $322.00 | |||
γ Enolase Antibody (NSE-P2): m-IgG Fc BP-HRP Bundle | sc-528366 | 200 µg Ab; 10 µg BP | $361.00 | |||
γ Enolase Antibody (NSE-P2): m-IgGκ BP-HRP Bundle | sc-520727 | 200 µg Ab, 40 µg BP | $361.00 | |||
γ Enolase Antibody (NSE-P2): m-IgG1 BP-HRP Bundle | sc-542894 | 200 µg Ab; 20 µg BP | $361.00 | |||
γ Enolase Antibody (NSE-P2) AC | sc-21737 AC | 500 µg/ml, 25% agarose | $424.00 | |||
γ Enolase Antibody (NSE-P2) HRP | sc-21737 HRP | 200 µg/ml | $322.00 | |||
γ Enolase Antibody (NSE-P2) FITC | sc-21737 FITC | 200 µg/ml | $336.00 | |||
γ Enolase Antibody (NSE-P2) PE | sc-21737 PE | 200 µg/ml | $349.00 | |||
γ Enolase Antibody (NSE-P2) Alexa Fluor® 488 | sc-21737 AF488 | 200 µg/ml | $364.00 | |||
γ Enolase Antibody (NSE-P2) Alexa Fluor® 546 | sc-21737 AF546 | 200 µg/ml | $364.00 | |||
γ Enolase Antibody (NSE-P2) Alexa Fluor® 594 | sc-21737 AF594 | 200 µg/ml | $364.00 | |||
γ Enolase Antibody (NSE-P2) Alexa Fluor® 647 | sc-21737 AF647 | 200 µg/ml | $364.00 | |||
γ Enolase Antibody (NSE-P2) Alexa Fluor® 680 | sc-21737 AF680 | 200 µg/ml | $364.00 | |||
γ Enolase Antibody (NSE-P2) Alexa Fluor® 790 | sc-21737 AF790 | 200 µg/ml | $364.00 |